Radioprotection and radiomitigation: from the bench to clinical practice
The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …
Adjunctive treatments for the prevention of chemotherapy-and radiotherapy-induced mucositis
M Thomsen, L Vitetta - Integrative Cancer Therapies, 2018 - journals.sagepub.com
Background: Chemoradiotherapy-associated mucositis can manifest as pain, inflammation,
dysphagia, diarrhea, weight loss, rectal bleeding, and infection. Mucositis is a major dose …
dysphagia, diarrhea, weight loss, rectal bleeding, and infection. Mucositis is a major dose …
Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic cancers
TA Lawrie, JT Green, M Beresford… - Cochrane Database …, 2018 - cochranelibrary.com
Background An increasing number of people survive cancer but a significant proportion
have gastrointestinal side effects as a result of radiotherapy (RT), which impairs their quality …
have gastrointestinal side effects as a result of radiotherapy (RT), which impairs their quality …
Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells
The intestinal epithelium has high intrinsic turnover rate, and the precise renewal of the
epithelium is dependent on the microenvironment. The intestine is innervated by a dense …
epithelium is dependent on the microenvironment. The intestine is innervated by a dense …
Mechanisms of inflammatory responses to radiation and normal tissues toxicity: clinical implications
Purpose: Cancer treatment is one of the most challenging diseases in the present era.
Among a few modalities for cancer therapy, radiotherapy plays a pivotal role in more than …
Among a few modalities for cancer therapy, radiotherapy plays a pivotal role in more than …
Alterations of the gut microbiome composition and lipid metabolic profile in radiation enteritis
Y Li, H Yan, Y Zhang, Q Li, L Yu, Q Li, C Liu… - Frontiers in cellular …, 2020 - frontiersin.org
Radiation enteritis (RE) is a common complication in cancer patients receiving radiotherapy.
Although studies have shown the changes of this disease at clinical, pathological and other …
Although studies have shown the changes of this disease at clinical, pathological and other …
A review on curability of cancers: more efforts for novel therapeutic options are needed
Cancer remains a major cause of death globally. Given its relapsing and fatal features,
curing cancer seems to be something hardly possible for the majority of patients. In view of …
curing cancer seems to be something hardly possible for the majority of patients. In view of …
The clinical and phenotypical assessment of seronegative villous atrophy; a prospective UK centre experience evaluating 200 adult cases over a 15-year period (2000 …
I Aziz, MF Peerally, JH Barnes, V Kandasamy… - Gut, 2017 - gut.bmj.com
Background Seronegative villous atrophy (SNVA) is commonly attributed to coeliac disease
(CD). However, there are other causes of SNVA. More recently angiotensin-2-receptor …
(CD). However, there are other causes of SNVA. More recently angiotensin-2-receptor …
Radiation enteritis: Diagnostic and therapeutic issues
L Loge, C Florescu, A Alves, B Menahem - Journal of visceral surgery, 2020 - Elsevier
Abdominal pelvic radiation therapy can induce acute or chronic lesions in the small bowel
wall, called radiation enteritis. Treatment of acute radiation enteritis is essentially …
wall, called radiation enteritis. Treatment of acute radiation enteritis is essentially …
Treatment-related complications of systemic therapy and radiotherapy
Importance Systemic therapy and radiotherapy can be associated with acute complications
that may require emergent care. However, there are limited data characterizing …
that may require emergent care. However, there are limited data characterizing …