Biologically active quinoline and quinazoline alkaloids part I

XF Shang, SL Morris‐Natschke, YQ Liu… - Medicinal research …, 2018 - Wiley Online Library
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …

Deep eutectic solvents (DESs) as eco-friendly and sustainable solvent/catalyst systems in organic transformations

S Khandelwal, YK Tailor, M Kumar - Journal of Molecular Liquids, 2016 - Elsevier
The development of efficient and environmentally benign synthetic protocols has attracted
increasing interest in modern organic syntheses in view of the growing concern over the …

Recent advances in sustainable synthesis of N-heterocycles following acceptorless dehydrogenative coupling protocol using alcohols

M Maji, D Panja, I Borthakur, S Kundu - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
The synthesis of heterocycles is an emerging area of chemical research considering their
high importance in pharmaceuticals, material chemistry, and natural product synthesis. The …

Recent developments in asymmetric multicomponent reactions

C de Graaff, E Ruijter, RVA Orru - Chemical Society Reviews, 2012 - pubs.rsc.org
Multicomponent reactions (MCRs) receive increasing attention because they address both
diversity and complexity in organic synthesis. Thus, in principle diverse sets of relatively …

Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue

I Khan, A Ibrar, W Ahmed, A Saeed - European journal of medicinal …, 2015 - Elsevier
The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids

K Nepali, S Sharma, M Sharma, PMS Bedi… - European journal of …, 2014 - Elsevier
A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …

Recent developments in the chemistry of quinazolinone alkaloids

UA Kshirsagar - Organic & biomolecular chemistry, 2015 - pubs.rsc.org
Quinazolinones, an important class of fused heterocyclic alkaloids has attracted high
attention in organic and medicinal chemistry due to their significant and wide range of …

Stereocontrolled domino reactions

H Pellissier - Chemical Reviews, 2013 - ACS Publications
A domino reaction has been defined by Tietze as a reaction involving two or more bond-
forming transformations that take place under the same reaction conditions, without adding …

[图书][B] Medicinal natural products: a biosynthetic approach

PM Dewick - 2002 - books.google.com
Medicinal Natural Products, Second Edition is a comprehensive guide providing information
on all classes of natural products in medicine. It builds upon fundamental chemical …

Recent advances in the structural library of functionalized quinazoline and quinazolinone scaffolds: Synthetic approaches and multifarious applications

I Khan, A Ibrar, N Abbas, A Saeed - European Journal of Medicinal …, 2014 - Elsevier
Drug development has been a principal driving force in the rapid maturation of the field of
medicinal chemistry during the past several decades. During this period, the intriguing and …