Circulating tumor cells and circulating tumor DNA: challenges and opportunities on the path to clinical utility
Recent technological advances have enabled the detection and detailed characterization of
circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from …
circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from …
Circulating tumor cell isolation, culture, and downstream molecular analysis
S Sharma, R Zhuang, M Long, M Pavlovic, Y Kang… - Biotechnology …, 2018 - Elsevier
Circulating tumor cells (CTCs) are a major contributor of cancer metastases and hold a
promising prognostic significance in cancer detection. Performing functional and molecular …
promising prognostic significance in cancer detection. Performing functional and molecular …
An organoid model of colorectal circulating tumor cells with stem cell features, hybrid EMT state and distinctive therapy response profile
ML De Angelis, F Francescangeli, C Nicolazzo… - Journal of Experimental …, 2022 - Springer
Abstract Background Circulating tumor cells (CTCs) are responsible for the metastatic
dissemination of colorectal cancer (CRC) to the liver, lungs and lymph nodes. CTCs rarity …
dissemination of colorectal cancer (CRC) to the liver, lungs and lymph nodes. CTCs rarity …
[HTML][HTML] Circulating tumor cells in hepatocellular carcinoma: single-cell based analysis, preclinical models, and clinical applications
Q Zhang, Y Rong, K Yi, L Huang, M Chen, F Wang - Theranostics, 2020 - ncbi.nlm.nih.gov
Circulating tumor cells (CTCs) are shed into the bloodstream from primary tumors and
metastatic lesions and provide significant information about tumor progression and …
metastatic lesions and provide significant information about tumor progression and …
Circulating tumor cell as the functional aspect of liquid biopsy to understand the metastatic cascade in solid cancer
LE Cortés-Hernández, Z Eslami-S… - Molecular aspects of …, 2020 - Elsevier
Metastasis is the main cause of death in patients with cancer. The molecular mechanisms
underlying the different metastasis steps are not yet fully known, partly because most studies …
underlying the different metastasis steps are not yet fully known, partly because most studies …
Ex Vivo Culture of CTCs: An Emerging Resource to Guide Cancer Therapy
S Maheswaran, DA Haber - Cancer research, 2015 - AACR
With increasing application of targeted therapies and the development of acquired
resistance, much attention is being focused on developing in vitro and in vivo patient …
resistance, much attention is being focused on developing in vitro and in vivo patient …
Circulating tumor microemboli: Progress in molecular understanding and enrichment technologies
Circulating tumor cells (CTCs) and their clusters, also known as circulating tumor
microemboli (CTM), have emerged as valuable tool that can provide mechanistic insights …
microemboli (CTM), have emerged as valuable tool that can provide mechanistic insights …
Ex vivo expansion and drug sensitivity profiling of circulating tumor cells from patients with small cell lung cancer
HL Lee, JF Chiou, PY Wang, LS Lu, CN Shen, HL Hsu… - Cancers, 2020 - mdpi.com
Simple Summary Small cell lung cancer (SCLC) is an overly aggressive cancer
characterized by rapid growth, early metastatic spread, and consequently reducing overall …
characterized by rapid growth, early metastatic spread, and consequently reducing overall …
Short-term ex vivo culture of CTCs from advance breast cancer patients: clinical implications
N Carmona-Ule, M González-Conde, C Abuín… - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumor cells (CTCs) are responsible for metastasis, they
represent tumor biology and have also predictive value for therapy monitoring and …
represent tumor biology and have also predictive value for therapy monitoring and …
[HTML][HTML] Liquid biopsy in pancreatic cancer: the beginning of a new era
With dismal survival rate pancreatic cancer remains one of the most aggressive and
devastating malignancy. Predominantly, due to the absence of a dependable methodology …
devastating malignancy. Predominantly, due to the absence of a dependable methodology …