As a major component of cell membrane lipids, Arachidonic acid (AA), being a major
component of the cell membrane lipid content, is mainly metabolized by three kinds of …

Observational, genetic, and experimental data indicate that triglyceride rich lipoproteins
(TRLs) likely participate causally in atherothrombosis. Yet, robust clinical trial evidence that …

Agonists of the nuclear receptor PPARγ are therapeutically used to combat hyperglycaemia
associated with the metabolic syndrome and type 2 diabetes. In spite of being effective in …

The PPARs are a subfamily of three ligand-inducible transcription factors, which belong to
the superfamily of nuclear hormone receptors. In mammals, the PPAR subfamily consists of …

Choline influences liver function, and the dietary requirement for this nutrient varies
depending on an individual's genotype and estrogen status. Understanding these individual …

Abstract Purpose of Review Reduction of serum low-density lipoprotein cholesterol (LDL-C)
levels by statins, ezetimibe and proprotein convertase subtilisin/kexin type 9 (PCSK9) …

Arachidonic acid can be oxygenated by a variety of different enzymes, including
lipoxygenases, cyclooxygenases, and cytochrome P450s, and can be converted to a …

Background and Purpose Nuciferine, an alkaloid found in Nelumbo nucifera leaves,
alleviates dyslipidemia in vivo. However, whether it improves liver injury in diabetic …

Ethnopharmacological relevance Cornus mas L.(cornelian cherry) fruits have been used for
centuries as traditional cuisine and folk medicine in various countries of Europe and Asia. In …

The intracellular fatty acid-binding proteins (FABPs) comprise a family of 14–15 kDa proteins
which bind long-chain fatty acids. A role for FABPs in fatty acid transport has been …