Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) remain as one
of the most global problematic metabolic diseases with rapidly increasing prevalence and …

Mounting evidence support the potential benefits of functional foods or nutraceuticals for
human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical …

Background Intrahepatic cholangiocarcinomas (ICCs) and extrahepatic
cholangiocarcinomas (ECCs) are highly lethal bile duct tumors. Their incidence can be …

Aging is a complex phenomenon characterized by the progressive loss of tissue and organ
function. The oxidative-stress theory of aging postulates that age-associated functional …

The intestinal reclamation of bile acids is crucial for the maintenance of their enterohepatic
circulation. The majority of bile acids are actively absorbed via specific transport proteins …

The incidence rate of hepatocellular carcinoma (HCC) is rising. It is one of the most common
cancers worldwide and accounts for substantial morbidity and mortality. Chronic hepatitis B …

One of the global burdens of health care is an alcohol-associated liver disease (ALD) and
liver-related death which is caused due to acute or chronic consumption of alcohol. Chronic …

Simple Summary In the context of liver disease, one of the more growing public health
problems is the transition from simple steatosis to non-alcoholic steatohepatitis. Profound …

Metabolic disorders have become among the most serious threats to human health, leading
to severe chronic diseases such as obesity, type 2 diabetes, and non-alcoholic fatty liver …

Mitochondrial dysfunction and oxidative stress-mediated inflammasome activation play
critical roles in the pathogenesis of the non-alcoholic fatty liver disease (NAFLD). Non …