The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

XY Fu-Shin, PSY Lee, L Yang, N Gao, Y Zhang… - Progress in retinal and …, 2022 - Elsevier
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

[HTML][HTML] The TGF-β/Smad4 signaling pathway in pancreatic carcinogenesis and its clinical significance

S Ahmed, AD Bradshaw, S Gera, MZ Dewan… - Journal of clinical …, 2017 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal human cancers due to its
complicated genomic instability. PDAC frequently presents at an advanced stage with …

Impaired inflammatory state of the endometrium: a multifaceted approach to endometrial inflammation. Current insights and future directions

A Drizi, D Djokovic, AS Laganà… - Menopause Review …, 2020 - termedia.pl
Methods A non-systematic review was done through a search on the following databases:
MEDLINE, EMBASE, Global Health, The Cochrane Library (Cochrane Database of …

Two faces of TGF‐beta1 in breast cancer

JM Zarzynska - Mediators of inflammation, 2014 - Wiley Online Library
Breast cancer (BC) is potentially life‐threatening malignancy that still causes high mortality
among women. Scientific research in this field is focused on deeper understanding of …

[HTML][HTML] Glial influences on BBB functions and molecular players in immune cell trafficking

MA Lecuyer, H Kebir, A Prat - … et Biophysica Acta (BBA)-Molecular Basis of …, 2016 - Elsevier
The blood–brain barrier (BBB) constitutes an elaborate structure formed by specialized
capillary endothelial cells, which together with pericytes and perivascular glial cells …

Group 3 pulmonary hypertension: from bench to bedside

N Singh, P Dorfmüller, OA Shlobin… - Circulation …, 2022 - Am Heart Assoc
Pulmonary hypertension (PH) because of chronic lung disease is categorized as Group 3
PH in the most recent classification system. Prevalence of these diseases is increasing over …

Methyl ferulic acid attenuates liver fibrosis and hepatic stellate cell activation through the TGF-β1/Smad and NOX4/ROS pathways

Q Cheng, C Li, C Yang, Y Zhong, D Wu, L Shi… - Chemico-biological …, 2019 - Elsevier
Liver fibrosis is a pathological wound-healing response caused by chronic liver damage due
to a virus, autoimmune disorder, or drugs. Hepatic stellate cells (HSCs) play an essential …

[HTML][HTML] The role of TGF-β and its receptors in gastrointestinal cancers

J Luo, XQ Chen, P Li - Translational oncology, 2019 - Elsevier
Early detection of gastrointestinal tumors improves patient survival. However, patients with
these tumors are typically diagnosed at an advanced stage and have poor prognosis. The …

A single combination gene therapy treats multiple age-related diseases

N Davidsohn, M Pezone, A Vernet… - Proceedings of the …, 2019 - National Acad Sciences
Comorbidity is common as age increases, and currently prescribed treatments often ignore
the interconnectedness of the involved age-related diseases. The presence of any one such …

Update of the diagnostic and therapeutic guidelines for gastro-entero-pancreatic neuroendocrine neoplasms (recommended by the Polish Network of Neuroendocrine …

B Kos-Kudła, W Foltyn, A Malczewska… - Endokrynologia …, 2022 - journals.viamedica.pl
Continuous progress in the diagnostics and treatment of neuroendocrine neoplasms
(NENs), the emerging results of new clinical trials, and the new guidelines issued by medical …