A mini review on pharmacological activities of oxadiazole and thiadiazole compounds

M Asif - Moroccan Journal of Chemistry, 2014 - revues.imist.ma
In the last few years, heterocyclic compounds have attracted strong interest and a lot of work
has been done on oxadiazole and thiadiazole ring. Oxadiazole and thiadiazole a five …

Microwave-assisted synthesis, molecular docking and antiproliferative activity of (3/5-aryl-1, 2, 4-oxadiazole-5/3-yl)(3, 4, 5-trimethoxyphenyl) methanone oxime …

Q Guan, D Feng, Z Bai, Y Cui, D Zuo, X Jiang… - …, 2015 - pubs.rsc.org
A series of (3/5-aryl-1, 2, 4-oxadiazole-5/3-yl)(3, 4, 5-trimethoxyphenyl) methanone oxime
derivatives were synthesized via a rapid and facile microwave-assisted synthesis method of …

Síntese e Bioatividade de 1, 2, 4-oxadiazóis

AP de Aguiar, FS Cunha - Revista Virtual de Química, 2015 - rvq-sub.sbq.org.br
A literatura reporta um número crescente de publicações envolvendo 1, 2, 4-oxadiazol ao
longo dos últimos anos, as quais tem tido como foco seu diversificado potencial …

[HTML][HTML] Preparação de 1, 2, 4-oxadiazol: sequência didática aplicada em disciplina de síntese orgânica na graduação

JLL Regueira, JJR de Freitas, JR Freitas Filho - Química Nova, 2016 - SciELO Brasil
Resumo 1, 2, 4-oxadiazoles are used in a wide range of applications, including medicinal
chemistry and chemistry of materials. However, this kind of oxadiazoles is not usually …

Design, Synthesis, Anticancer Activity and Molecular Docking Studies of 2, 5-Disubstituted-1, 3, 4-Oxadiazoles Containing Benzimidazole Moiety

R Katikireddy, R Kakkerla… - Letters in Organic …, 2020 - ingentaconnect.com
A series of benzimidazolyl-1, 3, 4-oxadiazoles (7a-k) were synthesized and evaluated for in
vitro anticancer activity against HeLa, MCF7, A549, and HEK293 cell lines. The results …

Synthesis and cytotoxic activity of (4-substituted-benzylidene)-(3-phenyl-1, 2, 4-oxadiazol-5-yl) methylamines

K Kucukoglu, M Tugrak, A Demirtas… - Pharmaceutical …, 2016 - Springer
This work was aimed at the synthesis and investigation of the cytotoxic activity of a series of
Schiff bases having (4-substituted-benzylidene)-(3-phenyl-1, 2, 4-oxadiazol-5-yl) …

N-(2-amino-5-chlorobenzoyl) benzamidoxime derivatives inhibit human leukemia cell growth

Y Nagahara, K Nagahara - Anticancer research, 2014 - ar.iiarjournals.org
Background/Aim: Amidoxime derivatives have been previously reported to have potent anti-
microbial and anti-tumor activity. Little is known about the tumor cell growth-inhibition …

Emerging Oxygen Based Heterocyclic Scaffolds as Potential Anticancer Candidates

D Kumar, P Sharma, MMM Lobe, S Kaur, TG Singh… - 2023 - preprints.org
Oxygen based heterocyclic moieties hold an ample range of therapeutic activities.
Heterocyclic molecules are nominated as vital components of an extensive array of …

Synthesis of novel pyrido[3,4‐d]pyrimidine‐thiazolidione‐1,2,4‐oxadiazoles as potent EGFR targeting anticancer agents

BD Varaprasadu, SB Haridasyam… - Journal of Heterocyclic … - Wiley Online Library
In this study, we designed and synthesized a number of novel pyrido [3, 4‐d] pyrimidine‐
thiazolidine‐1, 2, 4‐oxadiazole derivatives and investigated them in vitro for their inhibitory …

2-[4-[[2-(烷基氨甲酰基)-4-吡啶基] 氧基] 苯基] 乙酸的合成

于小越, 王远游, 赵桂森 - 化学试剂, 2013 - chinareagent.com.cn
本实验基于对抗肿瘤药物索拉菲尼的酰胺和恶二唑类衍生物的需求, 研究并设计合成了其重要
中间体, 2-[4-[[2-(烷基氨甲酰基)-4-吡啶基] 氧基] 苯基] 乙酸. 并对其物理, 化学性质进行评价 …