[HTML][HTML] Neurobiology and consequences of social isolation stress in animal model—A comprehensive review
The brain is a vital organ, susceptible to alterations under genetic influences and
environmental experiences. Social isolation (SI) acts as a stressor which results in …
environmental experiences. Social isolation (SI) acts as a stressor which results in …
[HTML][HTML] GABAergic inhibitory interneuron deficits in Alzheimer's disease: implications for treatment
Y Xu, M Zhao, Y Han, H Zhang - Frontiers in neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by severe
cognitive deficits and pathologically by amyloid plaques, neuronal loss, and neurofibrillary …
cognitive deficits and pathologically by amyloid plaques, neuronal loss, and neurofibrillary …
[HTML][HTML] Psycho-neuroendocrine-immune interactions in COVID-19: potential impacts on mental health
Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2). The impacts of the disease may be beyond the …
Syndrome Coronavirus 2 (SARS-CoV-2). The impacts of the disease may be beyond the …
[HTML][HTML] The impact of loneliness and social isolation on the development of cognitive decline and Alzheimer's disease
Alzheimer's Disease (AD) is the leading cause of dementia, observed at a higher incidence
in women compared with men. Treatments aimed at improving pathology in AD remain …
in women compared with men. Treatments aimed at improving pathology in AD remain …
Impact of spaceflight stressors on behavior and cognition: A molecular, neurochemical, and neurobiological perspective
The response of the human body to multiple spaceflight stressors is complex, but mounting
evidence implicate risks to CNS functionality as significant, able to threaten metrics of …
evidence implicate risks to CNS functionality as significant, able to threaten metrics of …
[HTML][HTML] The evidence for altered BDNF expression in the brain of rats reared or housed in social isolation: a systematic review
J Murínová, N Hlaváčová, M Chmelová… - Frontiers in behavioral …, 2017 - frontiersin.org
There is evidence that development and maintenance of neural connections are disrupted in
major mental disorders, which indicates that neurotrophic factors could play a critical role in …
major mental disorders, which indicates that neurotrophic factors could play a critical role in …
Potential neurobiological links between social isolation and Alzheimer's disease risk
E Drinkwater, C Davies… - European Journal of …, 2022 - Wiley Online Library
It is estimated that 40% of dementia cases could be prevented by modification of lifestyle
factors that associate with disease risk. One of these potentially modifiable lifestyle factors is …
factors that associate with disease risk. One of these potentially modifiable lifestyle factors is …
Adult social isolation leads to anxiety and spatial memory impairment: Brain activity pattern of COx and c-Fos
Social isolation during adulthood is a frequent problem that leads to a large variety of
adverse emotional and cognitive effects. However, most of the social isolation rodent …
adverse emotional and cognitive effects. However, most of the social isolation rodent …
The individual and combined effects of spaceflight radiation and microgravity on biologic systems and functional outcomes
Both microgravity and radiation exposure in the spaceflight environment have been
identified as hazards to astronaut health and performance. Substantial study has been …
identified as hazards to astronaut health and performance. Substantial study has been …
[HTML][HTML] Potential neurochemical and neuroendocrine effects of social distancing amidst the COVID-19 pandemic
Coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China, in December
2019. It was then declared a public health emergency of international concern on 30 th …
2019. It was then declared a public health emergency of international concern on 30 th …