2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease: The Task Force on sports cardiology and exercise in patients with …

A Pelliccia, S Sharma, S Gati, M Bäck… - European heart …, 2021 - academic.oup.com
or therapeutic medical strategies. However, the ESC Guidelines do not override in any way
whatsoever the individual responsibility of health professionals to make appropriate and …

Therapeutic approach for patients with catecholaminergic polymorphic ventricular tachycardia: state of the art and future developments

C van der Werf, AH Zwinderman, AAM Wilde - Europace, 2012 - academic.oup.com
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia
syndrome characterized by bidirectional or polymorphic ventricular arrhythmias under …

Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia

C van der Werf, PJ Kannankeril, F Sacher… - Journal of the American …, 2011 - jacc.org
Objectives: This study evaluated the efficacy and safety of flecainide in addition to
conventional drug therapy in patients with catecholaminergic polymorphic ventricular …

Catecholaminergic polymorphic ventricular tachycardia in children: analysis of therapeutic strategies and outcomes from an international multicenter registry

TM Roston, JM Vinocur, KR Maginot… - Circulation …, 2015 - Am Heart Assoc
Background—Catecholaminergic polymorphic ventricular tachycardia is an uncommon,
potentially lethal, ion channelopathy. Standard therapies have high failure rates and little is …

Arrhythmia characterization and long-term outcomes in catecholaminergic polymorphic ventricular tachycardia

RW Sy, MH Gollob, GJ Klein, R Yee, AC Skanes… - Heart Rhythm, 2011 - Elsevier
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is characterized
by adrenergically induced ventricular tachycardia (VT) associated with syncope and sudden …

[PDF][PDF] From gene-discovery to gene-tailored clinical management: 25 years of research in channelopathies and cardiomyopathies

L Crotti, P Brugada, H Calkins, P Chevalier, G Conte… - Europace, 2023 - academic.oup.com
In the early nineties, few years before the birth of Europace, the clinical and scientific world
of familial arrhythmogenic conditions was revolutionized by the identification of the first …

Familial evaluation in catecholaminergic polymorphic ventricular tachycardia: Disease penetrance and expression in cardiac ryanodine receptor mutation–carrying …

C van der Werf, I Nederend, N Hofman… - Circulation …, 2012 - Am Heart Assoc
Background—Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited
arrhythmia syndrome associated with mutations in the cardiac ryanodine receptor gene …

[HTML][HTML] Nadolol decreases the incidence and severity of ventricular arrhythmias during exercise stress testing compared with β1-selective β-blockers in patients with …

IS Leren, J Saberniak, E Majid, TF Haland… - Heart rhythm, 2016 - Elsevier
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an
inheritable cardiac disease predisposing to malignant ventricular arrhythmias. Objective We …

Ryanodine receptor physiology and its role in disease

JT Lanner - Calcium Signaling, 2012 - Springer
The ryanodine receptors (RyRs) is the major intracellular Ca 2+ release channel localized in
the plasma membrane of the endoplasmatic/sarcoplasmatic reticulum. RyR-mediated Ca 2+ …

How to perform and interpret provocative testing for the diagnosis of Brugada syndrome, long-QT syndrome, and catecholaminergic polymorphic ventricular …

MN Obeyesekere, GJ Klein, S Modi… - Circulation …, 2011 - Am Heart Assoc
Sudden cardiac death (SCD) is predominantly related to coronary artery disease and its
sequelae, cardiomyopathy, and congenital or valvular heart disease. No structural …