Circular RNA and its mechanisms in disease: from the bench to the clinic
B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …
to a new perspective regarding our understanding of cellular physiology and disease …
The bioinformatics toolbox for circRNA discovery and analysis
Circular RNAs (circRNAs) are a unique class of RNA molecule identified more than 40 years
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
Circular RNAs are miRNA sponges and can be used as a new class of biomarker
Circular RNAs (circRNAs) are a class of non-coding RNAs (ncRNAs) that are involved in
transcriptional and posttranscriptional gene expression regulation. The development of …
transcriptional and posttranscriptional gene expression regulation. The development of …
Circles reshaping the RNA world: from waste to treasure
J Liu, T Liu, X Wang, A He - Molecular cancer, 2017 - Springer
A new type of RNAs was identified from genes traditionally thought to express messenger or
linear ncRNA (noncoding RNA) only. They were subsequently named as circRNAs (circular …
linear ncRNA (noncoding RNA) only. They were subsequently named as circRNAs (circular …
microRNA‐based diagnostic and therapeutic applications in cancer medicine
LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …
Circular RNAs: a novel class of functional RNA molecules with a therapeutic perspective
Circular RNAs (circRNAs) are a subclass of non-coding RNAs that lack free 3′ and 5′
ends and, thus, exist as continuous loop RNAs. Such circular transcripts have been …
ends and, thus, exist as continuous loop RNAs. Such circular transcripts have been …
Mapping the entire functionally active endometrial microbiota
STUDY QUESTION Does endometrium harbour functionally active microorganisms and
whether the microbial composition differs between proliferative and mid-secretory phases …
whether the microbial composition differs between proliferative and mid-secretory phases …
Insights into the role of CircRNAs: biogenesis, characterization, functional, and clinical impact in human malignancies
Circular RNAs (circRNAs) are an evolutionarily conserved novel class of non-coding
endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be …
endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be …
New insight into circRNAs: characterization, strategies, and biomedical applications
XY Feng, SX Zhu, KJ Pu, HJ Huang, YQ Chen… - … Hematology & Oncology, 2023 - Springer
Circular RNAs (circRNAs) are a class of covalently closed, endogenous ncRNAs. Most
circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing …
circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing …
Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1
R March-Diaz, N Lara-Ureña, C Romero-Molina… - Nature Aging, 2021 - nature.com
Genetic Alzheimer's disease (AD) risk factors associate with reduced defensive amyloid β
plaque-associated microglia (AβAM), but the contribution of modifiable AD risk factors to …
plaque-associated microglia (AβAM), but the contribution of modifiable AD risk factors to …