Novel miRNA-mRNA interactions conserved in essential cancer pathways

E Andrés-León, I Cases, S Alonso, AM Rojas - Scientific reports, 2017 - nature.com
Cancer is a complex disease in which unrestrained cell proliferation results in tumour
development. Extensive research into the molecular mechanisms underlying tumorigenesis …

Transcriptomic Analysis in Human Macrophages Infected with Therapeutic Failure Clinical Isolates of Leishmania infantum

A Perea-Martínez, R García-Hernández… - ACS Infectious …, 2022 - ACS Publications
Leishmaniasis is one of the neglected tropical diseases with a worldwide distribution,
affecting humans and animals. In the absence of an effective vaccine, current treatment is …

Insights into circular RNAs: their biogenesis, detection, and emerging role in cardiovascular disease

Z Ward, J Pearson, S Schmeier, V Cameron… - RNA biology, 2021 - Taylor & Francis
Circular RNAs (circRNAs) are an evolutionarily conserved form of noncoding RNA with
covalently closed loop structures. Initial studies established a functional role for circRNAs as …

The RNA workbench: best practices for RNA and high-throughput sequencing bioinformatics in Galaxy

BA Grüning, J Fallmann, D Yusuf, S Will… - Nucleic acids …, 2017 - academic.oup.com
RNA-based regulation has become a major research topic in molecular biology. The
analysis of epigenetic and expression data is therefore incomplete if RNA-based regulation …

Disease‐Associated Circular RNAs: From Biology to Computational Identification

M Tang, L Kui, G Lu, W Chen - BioMed Research International, 2020 - Wiley Online Library
Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed continuous loop,
generated through various backsplicing events of pre‐mRNA. An accumulating number of …

High throughput sequencing of microRNA in rainbow trout plasma, mucus, and surrounding water following acute stress

H Ikert, MDJ Lynch, AC Doxey, JP Giesy… - Frontiers in …, 2021 - frontiersin.org
Circulating plasma microRNAs (miRNAs) are well established as biomarkers of several
diseases in humans and have recently been used as indicators of environmental exposures …

Innovative in Silico Approaches for Characterization of Genes and Proteins

GR Bhat, I Sethi, B Rah, R Kumar, D Afroze - Frontiers in Genetics, 2022 - frontiersin.org
Bioinformatics is an amalgamation of biology, mathematics and computer science. It is a
science which gathers the information from biology in terms of molecules and applies the …

Retracted: Protective impacts of circular RNA VMA21 on lipopolysaccharide‐engendered WI‐38 cells injury via mediating microRNA‐142‐3p

P Yang, R Gao, W Zhou, A Han - Biofactors, 2020 - Wiley Online Library
CircRNA derived from vacuolar ATPase assembly factor (circVMA21) is a newly‐researched
circRNA, which is reported to adjust the degeneration of intervertebral disc. But, function of …

Specific microRNAs found in extracellular matrix vesicles regulate proliferation and differentiation in growth plate chondrocytes

NC Asmussen, DJ Cohen, Z Lin, MJ McClure… - Calcified Tissue …, 2021 - Springer
Matrix vesicles (MVs) are extracellular organelles produced by growth plate cartilage cells in
a zone-specific manner. MVs are similar in size to exosomes, but they are tethered to the …

Molecular alterations during larval development of Haemonchus contortus in vitro are under tight post-transcriptional control

G Ma, T Wang, PK Korhonen, CS Ang… - International journal for …, 2018 - Elsevier
In this study, we explored the molecular alterations in the developmental switch from the L3
to the exsheathed L3 (xL3) and to the L4 stage of Haemonchus contortus in vitro using an …