[HTML][HTML] Antioxidant defence systems and oxidative stress in poultry biology: An update

PF Surai, II Kochish, VI Fisinin, MT Kidd - Antioxidants, 2019 - mdpi.com
Poultry in commercial settings are exposed to a range of stressors. A growing body of
information clearly indicates that excess ROS/RNS production and oxidative stress are …

[HTML][HTML] Metabolomics of type 1 and type 2 diabetes

B Arneth, R Arneth, M Shams - International journal of molecular sciences, 2019 - mdpi.com
Type 1 and type 2 diabetes mellitus (DM) are chronic diseases that affect nearly 425 million
people worldwide, leading to poor health outcomes and high health care costs. High …

Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis

V Calabrese, A Santoro, D Monti, R Crupi… - Free Radical Biology …, 2018 - Elsevier
In order to better understand the pathogenesis of Parkinson's Disease (PD) it is important to
consider possible contributory factors inherent to the aging process, as age-related changes …

[HTML][HTML] Neuroinflammation and neurohormesis in the pathogenesis of Alzheimer's disease and Alzheimer-linked pathologies: modulation by nutritional mushrooms

A Trovato Salinaro, M Pennisi, R Di Paola, M Scuto… - Immunity & …, 2018 - Springer
Human life develops and expands not only in time and space, but also in the retrograde
permanent recollection and interweaving of memories. Therefore, individual human identity …

[HTML][HTML] The hallmarks of glioblastoma: Heterogeneity, intercellular crosstalk and molecular signature of invasiveness and progression

F Torrisi, C Alberghina, S D'Aprile, AM Pavone… - Biomedicines, 2022 - mdpi.com
In 2021 the World Health Organization published the fifth and latest version of the Central
Nervous System tumors classification, which incorporates and summarizes a long list of …

NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis

N Braidy, Y Liu - Experimental Gerontology, 2020 - Elsevier
Nicotinamide adenine dinucleotide (NAD+) is an essential pyridine nucleotide that is
present in all living cells. NAD+ acts as an important cofactor and substrate for a multitude of …

Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease

M Pennisi, R Crupi, R Di Paola… - Journal of …, 2017 - Wiley Online Library
Alzheimer disease (AD) is a progressive neurodegenerative disorder leading to cognitive
decline, neuropsychiatric symptoms, disability, caregiver burden, and premature death. It …

[HTML][HTML] The analysis of miRNA expression profiling datasets reveals inverse microRNA patterns in glioblastoma and Alzheimer's disease

S Candido, G Lupo, M Pennisi… - Oncology …, 2019 - spandidos-publications.com
There is recent evidence to indicate the existence of an inverse association between the
incidence of neurological disorders and cancer development. Concurrently, the …

Mitochondria, the NLRP3 inflammasome, and sirtuins in type 2 diabetes: new therapeutic targets

S Rovira-Llopis, N Apostolova, C Banuls… - Antioxidants & Redox …, 2018 - liebertpub.com
Significance: Type 2 diabetes mellitus and hyperglycemia can lead to the development of
comorbidities such as atherosclerosis and microvascular/macrovascular complications. Both …

[HTML][HTML] Nitric oxide-mediated posttranslational modifications: impacts at the synapse

SA Bradley, JR Steinert - Oxidative medicine and cellular longevity, 2016 - hindawi.com
Nitric oxide (NO) is an important gasotransmitter molecule that is involved in numerous
physiological processes throughout the nervous system. In addition to its involvement in …