Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …

Obesity has been associated with oxidative stress. Obese patients are at increased risk for
diabetic cognitive dysfunction, indicating a pathological link between obesity, oxidative …

Mitochondria play a vital role in the nervous system, as they are responsible for generating
energy in the form of ATP and regulating cellular processes such as calcium (Ca 2+) …

Ferroptosis is a newly discovered form of iron-dependent oxidative cell death and drives the
loss of neurons in spinal cord injury (SCI). Mitochondrial damage is a critical contributor to …

Neurodegenerative diseases comprise a wide spectrum of pathologies characterized by
progressive loss of neuronal functions and structures. Despite having different genetic …

The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …

Mitochondria are the primary source of energy production and are implicated in a wide
range of biological processes in most eukaryotic cells. Skeletal muscle heavily relies on …

Mitochondria are the only organelles, along with the nucleus, that have their own DNA.
Mitochondrial DNA (mtDNA) is a double-stranded circular molecule of~ 16.5 kbp that can …

Healthy brain activity requires precise ion and energy management creating a strong
reliance on mitochondrial function. Age-related neurodegeneration leads to a decline in …

Strong evidence suggests a correlation between degeneration and mitochondrial deficiency.
Typical cases of degeneration can be observed in physiological phenomena (ie, ageing) as …