Hypertension is regarded as the most prominent risk factor for cardiovascular diseases,
which have become a primary cause of death, and recent research has demonstrated that …

Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of
mortality worldwide, and its importance is further emphasized in the context of the novel …

Despite the success of renin-angiotensin system (RAS) blockade by angiotensin-converting
enzyme (ACE) inhibitors and angiotensin II type 1 receptor (AT1R) blockers, current …

Complex and bidirectional interactions between the renin–angiotensin system (RAS) and
autonomic nervous system have been well established for cardiovascular regulation under …

Innate immunity and chronic inflammation are involved in atherosclerosis and
atherothrombosis, leading to target organ damage in essential hypertension (EH). However …

Atherosclerosis has complex pathogenesis, which involves at least three serious aspects:
inflammation, lipid metabolism alterations, and endothelial injury. There are no effective …

Mineralocorticoid excess commonly leads to hypertension (HTN) and kidney disease. In our
study, we used single-cell expression and chromatin accessibility tools to characterize the …

The occurrence of a novel coronavirus known as severe acute respiratory syndrome-
coronavirus-2 (SARS-CoV-2), created a serious challenge worldwide. SARS-CoV-2 has …

Since December 2019, the infection of the new coronavirus (COVID-19) caused an outbreak
of new coronavirus pneumonia in Wuhan, China, and caused great public concern. Both …

SARS‐CoV‐2 interacting with its receptor, angiotensin‐converting enzyme 2 (ACE2), turns
the host response to viral infection into a dysregulated uncontrolled inflammatory response …