Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment

E Choy, K Ganeshalingam, AG Semb… - …, 2014 - academic.oup.com
Risk of cardiovascular (CV) disease is increased among RA patients. High inflammatory
burden associated with RA appears to be a key driver of the increased cardiovascular risk …

[HTML][HTML] Role of cytokines and chemokines in non-alcoholic fatty liver disease

V Braunersreuther, GL Viviani, F Mach… - World journal of …, 2012 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) includes a variety of histological conditions
(ranging from liver steatosis and steatohepatitis, to fibrosis and hepatocarcinoma) that are …

Polyphenols and health: Moving beyond antioxidants

G Chiva-Blanch, F Visioli - Journal of Berry Research, 2012 - content.iospress.com
Diets in which plant foods, including berries, provide a relevant portion of caloric intake are
associated with a reduced risk of certain degenerative diseases like cancer and …

Endothelial function and endothelial progenitor cells in systemic lupus erythematosus

A Mak, JKY Chan - Nature Reviews Rheumatology, 2022 - nature.com
The observations that traditional cardiovascular disease (CVD) risk factors fail to fully
account for the excessive cardiovascular mortality in patients with systemic lupus …

Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1 β via the nucleotide-binding domain …

P Ruscitti, P Cipriani, P Di Benedetto… - Clinical & …, 2015 - academic.oup.com
A better understanding about the mechanisms involved in the pathogenesis of type 2
diabetes mellitus (T2D) showed that inflammatory cytokines such as tumour necrosis factor …

The lipid paradox as a metabolic checkpoint and its therapeutic significance in ameliorating the associated cardiovascular risks in rheumatoid arthritis patients

T Behl, I Kaur, A Sehgal, G Zengin, C Brisc… - International journal of …, 2020 - mdpi.com
While the most common manifestations associated with rheumatoid arthritis (RA) are
synovial damage and inflammation, the systemic effects of this autoimmune disorder are life …

Berberine ameliorates collagen-induced arthritis in rats associated with anti-inflammatory and anti-angiogenic effects

Z Wang, Z Chen, S Yang, Y Wang, Z Huang, J Gao… - Inflammation, 2014 - Springer
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by inflammation
and joint destruction. In this study, we explored the effect of berberine on rats with bovine …

Sex-specific effects of the Nlrp3 inflammasome on atherogenesis in LDL receptor-deficient mice

S Chen, JL Markman, K Shimada, TR Crother… - Basic to Translational …, 2020 - jacc.org
In the Ldlr-/-mouse model of atherosclerosis, female Nlrp3-/-bone marrow chimera and
Nlrp3-/-mice developed significantly smaller lesions in the aortic sinus and decreased lipid …

Cardiovascular magnetic resonance detects silent heart disease missed by echocardiography in systemic lupus erythematosus

S Mavrogeni, L Koutsogeorgopoulou… - Lupus, 2018 - journals.sagepub.com
Background Accurate diagnosis of cardiovascular involvement in systemic lupus
erythematosus (SLE) remains challenging, due to limitations of echocardiography. We …

Inflammation and dementia: Using rheumatoid arthritis as a model to develop treatments?

A Mason, C Holmes, CJ Edwards - Autoimmunity reviews, 2018 - Elsevier
Dementia is a major international public health problem which looks set to grow as the
ageing population increases. Despite large amounts of investment there has been relatively …