Osteoporosis has been defined as the silent disease of the 21st century, becoming a public
health risk due to its severity, chronicity and progression and affecting mainly …

Osteogenesis imperfecta (OI) is the most common inherited form of bone fragility and
includes a heterogenous group of genetic disorders which most commonly result from …

Rationale: The impaired function of endogenous bone marrow mesenchymal stem cells
(BMMSCs) is a determinant in the development of osteoporosis (OP). Recent researches …

The most widely used medications for the treatment of osteoporosis are currently
bisphosphonates (BPs) and denosumab (Dmab). Both are antiresorptives, thus targeting the …

Osteoporosis (OP) is a bone metabolic disease, is characterized by degeneration of bone
structure and decreased bone mass. It happens in more than 1/3 women and 1/5 men of …

With an increase in the ageing population worldwide, the prevalence of osteoporosis
increases at an alarming rate in both male and female irrespective of their ethnicity. At …

Imbalance of bone homeostasis induces bone degenerative diseases such as osteoporosis.
Hedgehog (Hh) signaling plays critical roles in regulating the development of limb and joint …

Background Chronic periodontitis is a multifactorial inflammatory disease resulting in
patients exhibiting high levels of inflammatory factors causing systemic inflammatory bone …

Calcium is vital for life, and extracellular calcium concentrations must constantly be
maintained within a precise concentration range. Low serum calcium (hypocalcemia) occurs …

Objective Senile osteoporosis is one of the most common age-related diseases worldwide.
Accumulating evidences have indicated that young blood can reverse age-related …