[HTML][HTML] Hierarchical ultrastructure: an overview of what is known about tendons and future perspective for tendon engineering
Abnormal tendons are rarely ever repaired to the natural structure and morphology of
normal tendons. To better guide the repair and regeneration of injured tendons through a …
normal tendons. To better guide the repair and regeneration of injured tendons through a …
Impact of aging on tendon homeostasis, tendinopathy development, and impaired healing
Aging is a complex and progressive process where the tissues of the body demonstrate a
decreased ability to maintain homeostasis. During aging, there are substantial cellular and …
decreased ability to maintain homeostasis. During aging, there are substantial cellular and …
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1
J Lu, X Yang, C He, Y Chen, C Li, S Li, Y Chen, Y Wu… - Acta Biomaterialia, 2023 - Elsevier
The regenerative capabilities including self-renewal, migration and differentiation potentials
shift from the embryonic phase to the mature period of endogenous tendon stem/progenitor …
shift from the embryonic phase to the mature period of endogenous tendon stem/progenitor …
An asymmetric chitosan scaffold for tendon tissue engineering: In vitro and in vivo evaluation with rat tendon stem/progenitor cells
E Chen, L Yang, C Ye, W Zhang, J Ran, D Xue… - Acta Biomaterialia, 2018 - Elsevier
The poor healing capacity and typically incomplete regeneration of injured tendons has
made tendon repair as a primary clinical concern. Several methods for repairing injured …
made tendon repair as a primary clinical concern. Several methods for repairing injured …
The rat Achilles and patellar tendons have similar increases in mechanical properties but become transcriptionally divergent during postnatal development
D Steffen, A Avey, MJ Mienaltowski… - The Journal of …, 2023 - Wiley Online Library
The molecular events that drive post‐natal tendon development are poorly characterized. In
this study, we profiled morphological, mechanical, and transcriptional changes in the rat …
this study, we profiled morphological, mechanical, and transcriptional changes in the rat …
[HTML][HTML] Tendon stem/progenitor cell subpopulations and their implications in tendon biology
Tendon harbors a cell population that possesses stem cell characteristics such as
clonogenicity, multipotency and self-renewal capacity, commonly referred to as tendon …
clonogenicity, multipotency and self-renewal capacity, commonly referred to as tendon …
Targeting senescent tendon stem/progenitor cells to prevent or treat age-related tendon disorders
H Wang, GC Dai, YJ Li, MH Chen, PP Lu… - Stem Cell Reviews and …, 2023 - Springer
Age-related tendon disorder, a primary motor system disease, is characterized by biological
changes in the tendon tissue due to senescence and seriously affects the quality of life of the …
changes in the tendon tissue due to senescence and seriously affects the quality of life of the …
SM04755, a small‐molecule inhibitor of the Wnt pathway, as a potential topical treatment for tendinopathy
V Deshmukh, T Seo, AL O'Green… - Journal of …, 2021 - Wiley Online Library
The Wnt pathway is upregulated in tendinopathy, affecting inflammation and tenocyte
differentiation. Given its potential role in tendinopathy, this signaling pathway may be a …
differentiation. Given its potential role in tendinopathy, this signaling pathway may be a …
Mesenchymal stem cells in tendon repair and regeneration: basic understanding and translational challenges
DJ Leong, HB Sun - Annals of the New York Academy of …, 2016 - Wiley Online Library
Tendon injuries are common and present a clinical challenge because they often respond
poorly to treatment and require prolonged rehabilitation. Current treatments often do not …
poorly to treatment and require prolonged rehabilitation. Current treatments often do not …
Heart functional and structural compendium of cardiosplenic and cardiorenal networks in acute and chronic heart failure pathology
Heart failure (HF) secondary to myocardial infarction (MI) is linked to kidney complications
that comprise cellular, structural, functional, and survival indicators. However, HF research is …
that comprise cellular, structural, functional, and survival indicators. However, HF research is …