Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs
DR Tompa, A Immanuel, S Srikanth… - International journal of …, 2021 - Elsevier
The infectious microscopic viruses invade living cells to reproduce themselves, and causes
chronic infections such as HIV/AIDS, hepatitis B and C, flu, etc. in humans which may lead to …
chronic infections such as HIV/AIDS, hepatitis B and C, flu, etc. in humans which may lead to …
Molecular mechanisms of viral oncogenesis in humans
NA Krump, J You - Nature Reviews Microbiology, 2018 - nature.com
Viral infection is a major contributor to the global cancer burden. Recent advances have
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …
Anti-HCV, nucleotide inhibitors, repurposing against COVID-19
AA Elfiky - Life sciences, 2020 - Elsevier
Aims A newly emerged Human Coronavirus (HCoV) is reported two months ago in Wuhan,
China (COVID-19). Until today> 2700 deaths from the 80,000 confirmed cases reported …
China (COVID-19). Until today> 2700 deaths from the 80,000 confirmed cases reported …
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeutic drug target using a computational approach
Abstract Background The Severe acute respiratory syndrome-related coronavirus 2 (SARS-
CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the …
CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the …
Sofosbuvir as a potential alternative to treat the SARS-CoV-2 epidemic
R Jácome, JA Campillo-Balderas, S Ponce de León… - Scientific Reports, 2020 - nature.com
As of today, there is no antiviral for the treatment of the SARS-CoV-2 infection, and the
development of a vaccine might take several months or even years. The structural …
development of a vaccine might take several months or even years. The structural …
Ferrocene derivatives as anti-infective agents
BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
Antisense antimicrobial therapeutics
EK Sully, BL Geller - Current opinion in microbiology, 2016 - Elsevier
Highlights•A LNA–DNA hybrid oligomer (miravirsen) is targeted to a host micro RNA instead
of the pathogen (hepatitis C virus)•Miravirsen demonstrates broad antiviral activity against …
of the pathogen (hepatitis C virus)•Miravirsen demonstrates broad antiviral activity against …
Hepatitis C–New drugs and treatment prospects
M Zając, I Muszalska, A Sobczak, A Dadej… - European journal of …, 2019 - Elsevier
Hepatitis C virus (HCV) affects approx. 3% of the world's population and accounts for ca 300
000 deaths per year. 80% of individuals with HCV develop chronic symptoms which, when …
000 deaths per year. 80% of individuals with HCV develop chronic symptoms which, when …
[HTML][HTML] Nucleotide and nucleoside-based drugs: past, present, and future
AA Al Awadh - Saudi Journal of Biological Sciences, 2022 - Elsevier
Nucleotide and nucleoside-based analogue drugs are widely used for the treatment of both
acute and chronic viral infections. These drugs inhibit viral replication due to one or more …
acute and chronic viral infections. These drugs inhibit viral replication due to one or more …
Identification of effective anti-HCV and anti-HIV royal jelly constituents and their acute toxicity evaluation in Albino rats
NH Habashy, AF Hamouda, MMA Serie - Food and Chemical Toxicology, 2023 - Elsevier
Few studies on royal jelly's (RJ) antiviral activities and toxicity have been conducted. Here,
we investigated the antioxidant properties of RJ that was fractionated into soluble fraction …
we investigated the antioxidant properties of RJ that was fractionated into soluble fraction …