With the development of modern chemistry and biology, non-proteinogenic amino acids
(NPAAs) have become a powerful tool for developing peptide-based drug candidates. Drug …

Systemic lupus erythematosus (SLE) is an autoimmune chronic inflammatory disease of
unknown etiology, although genetic and environmental factors appear to contribute to its …

A causal link between viral infections and autoimmunity has been studied for a long time
and the role of some viruses in the induction or exacerbation of systemic lupus …

The tumor suppressor p53 is the most frequently mutated gene in human cancers. Most of
the mutations are missense leading to loss of p53 function in inducing apoptosis and …

Dendritic cells (DCs) function as a link between innate and adaptive immune responses.
Retroviruses HIV-1 and HTLV-1 modulate DCs to their advantage and utilize them to …

Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterized
primarily by immune-mediated destruction of exocrine tissues, such as those of the salivary …

Human T-cell lymphotropic virus type-1 (HTLV-1) has a large global burden and in some key
communities, such as Indigenous Australians living in remote areas, greater than 45% of …

It is generally accepted that certain viral infections can trigger the development of
autoimmune diseases. However, the exact mechanisms by which these viruses induce …

Immune homeostasis is a tightly regulated system that is critical for defense against invasion
by foreign pathogens and protection from self-reactivity for the survival of an individual. How …

Despite the prognostic value of arterial stiffness (AS) and pulsatile hemodynamics (PH) for
cardiovascular morbidity and mortality, epigenetic modifications that contribute to AS/PH …