Photodynamic therapy of malignant brain tumours: A complementary approach to conventional therapies

D Bechet, SR Mordon, F Guillemin… - Cancer treatment …, 2014 - Elsevier
The poor outcome of primary malignant brain tumours is predominantly due to local invasion
and local recurrence and their prognosis is highly dependent on the degree of resection …

Photodynamic therapy of brain tumors and novel optical coherence tomography strategies for in vivo monitoring of cerebral fluid dynamics

A Abdurashitov, V Tuchin… - Journal of Innovative …, 2020 - World Scientific
Photodynamic therapy (PDT) is a promising tool for least-invasive alternative methods for
the treatment of brain tumors. The newly discovered PDT-induced opening of the blood …

Monitoring of singlet oxygen is useful for predicting the photodynamic effects in the treatment for experimental glioma

J Yamamoto, S Yamamoto, T Hirano, S Li, M Koide… - Clinical cancer …, 2006 - AACR
Abstract Purpose: Singlet oxygen (1O2) generated in photodynamic therapy (PDT) plays a
very important role in killing tumor cells. Using a new near-IR photomultiplier tube system …

Evaluation of photodynamic therapy near functional brain tissue in patients with recurrent brain tumors

MH Schmidt, GA Meyer, KW Reichert, J Cheng… - Journal of neuro …, 2004 - Springer
Introduction: Photodynamic therapy (PDT) involves the selective retention of a
photosensitizer that upon activation with light mediates tumor cell destruction via the …

Cerebral edema following photodynamic therapy using endogenous and exogenous photosensitizers in normal brain

MS Mathews, D Chighvinadze, HM Gach… - Lasers in surgery …, 2011 - Wiley Online Library
Abstract Background and Objective Failure of treatment for high‐grade gliomas is usually
due to local recurrence at the site of surgical resection indicating that a more aggressive …

The optimization of fluorescence imaging of brain tumor tissue differentiated from brain edema—in vivo kinetic study of 5-aminolevulinic acid and talaporfin sodium

T Tsurubuchi, A Zaboronok, T Yamamoto… - Photodiagnosis and …, 2009 - Elsevier
OBJECTIVE: We aimed to clarify the optimal timing for the fluorescence imaging of brain
tumor tissue differentiated from brain edema after the administration of photosensitizers …

New light on the brain: the role of photosensitizing agents and laser light in the management of invasive intracranial tumors

MS Eljamel - Technology in Cancer Research & Treatment, 2003 - journals.sagepub.com
Invasive intracranial tumors, particularly malignant gliomas, are very difficult to eradicate
surgically and carry a dismal prognosis. The vast majority relapse locally indicating that their …

Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas—Experimental study on rat and human cell cultures

LM Neumann, K Beseoglu, PJ Slotty, B Senger… - Photodiagnosis and …, 2016 - Elsevier
Background Incomplete resection of pituitary adenomas may result in recurrence. As
adjuvant irradiation is not riskless, alternative treatment options should be investigated. 5 …

Neural stem cell transplantation in cold lesion: a novel approach for the investigation of brain trauma and repair

Z Lacza, E Horváth, DW Busija - Brain Research Protocols, 2003 - Elsevier
We developed a new neural transplantation protocol for the investigation of the repair of
brain trauma. Cortical lesion was induced by touching a cold (− 60° C) metal stamp to the …

光动力学疗法与间质内化疗联合治疗脑胶质瘤的临床研究

陈利锋, 柯以铨, 杨志林, 王松青, 徐如祥 - 第一军医大学学报, 2005 - cqvip.com
目的探讨显微手术后联合光动力学疗法(PDT) 与局部间质化疗对脑胶质瘤的疗效. 方法28
例脑胶质瘤患者术中尽可能多地切除肿瘤后行PDT 首次照射, 并在残瘤腔内埋置Ommaya 囊 …