[HTML][HTML] Computational Studies Applied to Linalool and Citronellal Derivatives Against Alzheimer's and Parkinson's Disorders: A Review with Experimental Approach

PR da Silva, JC de Andrade, NF de Sousa… - Current …, 2023 - ncbi.nlm.nih.gov
Alzheimer's and Parkinson's are neurodegenerative disorders that affect a great number of
people around the world, seriously compromising the quality of life of individuals, due to …

In Vivo Assays for Amyloid-Related Diseases

A Espargaró, I Álvarez-Berbel… - Annual Review of …, 2024 - annualreviews.org
Amyloid-related diseases, such as Alzheimer's and Parkinson's disease, are devastating
conditions caused by the accumulation of abnormal protein aggregates known as amyloid …

Chronic exposure to environmentally relevant concentrations of guanylurea induces neurotoxicity of Danio rerio adults

GA Elizalde-Velázquez, LM Gómez-Oliván… - Science of the Total …, 2022 - Elsevier
Recent studies have shown guanylurea (GUA) alters the growth and development of fish,
induces oxidative stress, and disrupts the levels and expression of several genes …

Ameliorative effects of probiotics in AlCl3-induced mouse model of Alzheimer's disease

M Hamid, S Zahid - Applied Microbiology and Biotechnology, 2023 - Springer
In recent years, gut microbiome alterations have been linked with complex underlying
mechanisms of neurodegenerative disorders including Alzheimer's disease (AD). The gut …

DE-71 affected the cholinergic system and locomotor activity via disrupting calcium homeostasis in zebrafish larvae

X Wang, L Zhao, Q Shi, Y Guo, J Hua, J Han, L Yang - Aquatic Toxicology, 2022 - Elsevier
Polybrominated diphenyl ethers (PBDEs) can induce neurotoxicity, but the mechanism of
their toxicity on the cholinergic system and locomotion behavior remains unclear. In this …

Neurotoxic effects of chloroquine and its main transformation product formed after chlorination

S Hu, J Zhao, S Fang, K Guo, W Qi, H Liu - Science of The Total …, 2024 - Elsevier
Pharmaceutical transformation products (TPs) generated during wastewater treatment have
become an environmental concern. However, there is limited understanding regarding the …

Sex differences shape zebrafish performance in a battery of anxiety tests and in response to acute scopolamine treatment

BE Dos Santos, ACVV Giacomini, L Marcon… - Neuroscience …, 2021 - Elsevier
Sex differences influence human and animal behavioral and pharmacological responses.
The zebrafish (Danio rerio) is a powerful, popular model system in neuroscience and drug …

[HTML][HTML] Oxidative stress as the trigger for menthol-induced developmental alterations in zebrafish (Danio rerio) model

P Carneiro, R Vieira, C Venâncio, L Felix - Journal of Environmental …, 2022 - Elsevier
Menthol is a natural origin organic compound obtained from the peppermint plant whose
effects at the embryonic development level are not completely known. In this work, the …

The impact of ammonia and microcystin-LR on neurobehavior and glutamate/gamma-aminobutyric acid balance in female zebrafish (Danio rerio): ROS and …

Y He, K Ouyang, H Yang, L Wang, X Wang, D Li… - Science of The Total …, 2024 - Elsevier
Ammonia and microcystin-LR (MC-LR) are both toxins that can be in eutrophic waters during
cyanobacterial blooms. While previous studies have focused on the effects of ammonia …

Toxicological impact of SARS-CoV-2 on the health of the neotropical fish, Poecilia reticulata

G Malafaia, MAI Ahmed, SS de Souza, FNE Rezende… - Aquatic Toxicology, 2022 - Elsevier
There have been significant impacts of the current COVID-19 pandemic on society including
high health and economic costs. However, little is known about the potential ecological risks …