Nuclear receptors (NRs) are transcription factors actively involved in many aspects of human
physiology and pathology, serving as sensors of stimuli, master regulators of downstream …

Metastatic prostate cancer is associated with considerable morbidity and mortality. Standard
treatment for non-metastatic prostate cancer, to prevent metastatic progression, is androgen …

Background Current cancer mortality figures are important for disease management and
resource allocation. We estimated mortality counts and rates for 2020 in the European Union …

Background: Artificial intelligence (AI) is the way to model human intelligence to accomplish
certain tasks without much intervention of human beings. The term AI was first used in 1956 …

Drug-induced liver injury (DILI) and cardiotoxicity (DICT) are major adverse effects triggered
by many clinically important drugs. To provide an alternative to in vivo toxicity testing, the US …

Simple Summary Estrogens are steroid hormones that interact with nuclear receptors (ERα
and ERβ) and a membrane G-protein-coupled receptor (GPER) to regulate multiple …

Background Castration-resistant prostate cancer (CRPC) is refractory to hormone treatment.
This study aims to explore the effect and underlying mechanisms of immunoproteasome …

Receptor-related orphan receptor γ (RORγ) has emerged as an attractive therapeutic target
for the treatment of cancer and inflammatory diseases. Herein, we report our effort on the …

Peptides are strings of approximately 2–50 amino acids, which have gained huge attention
for theranostic applications in cancer research due to their various advantages including …

Simple Summary This paper is one in a series of articles that investigate the functional forms
of autophagy induced in tumor cells in response to various chemotherapeutic modalities …