Background: After application of iodinated contrast media (CM), a pronounced deterioration
of the microcirculation in skin and myocardium was reported. Clinically, the repeated …

BACKGROUND AND PURPOSE: Intracarotid arterial infusion of nonionic, low-osmolal
iohexol contrast medium has been associated with increased intracranial hemorrhage in a …

Iodinated contrast media (CM) are widely used in diagnostic imaging and therapeutic
interventional procedures of everyday clinical practice and are associated with multiple …

Radiographic contrast media (RCM) can vary widely in their physicochemical properties, eg
the iodine concentration, osmolality, molecule structure, chemotoxicity, hydrophilicity …

INTRODUCTION: Clinical complications like thrombosis or anaphylaxis have been
described to go along with the intravenous or intra-arterial injection of iodinated contrast …

Radiographic contrast media can lead to drastic changes of the morphology of erythrocytes.
The change of the erythrocyte morphology is associated with a decreased deformability …

A type-dependent chemotoxic effect of radiographic contrast media on erythrocytes and
endothelial cells was reported several times. While mechanisms of toxicity are still unclear …

After intra-arterial administration of several radiographic contrast media (RCM) a disorder of
the downstream microcirculation with regard to blood flow velocity in microvessels and to …

It is well known that clinically relevant concentrations of iodine-containing radiographic
contrast media (CM) induce morphological changes in human erythrocytes. However, there …

The incubation of erythrocytes (RBC) or endothelial cells (HUVEC) in radiographic contrast
media (RCM) could induce morphological alterations of or at the cell membranes, eg the …