Demographic history, selection and functional diversity of the canine genome
The domestic dog represents one of the most dramatic long-term evolutionary experiments
undertaken by humans. From a large wolf-like progenitor, unparalleled diversity in …
undertaken by humans. From a large wolf-like progenitor, unparalleled diversity in …
A revised diagnostic classification of canine glioma: towards validation of the canine glioma patient as a naturally occurring preclinical model for human glioma
Abstract The National Cancer Institute-led multidisciplinary Comparative Brain Tumor
Consortium (CBTC) convened a glioma pathology board, comprising both veterinarian and …
Consortium (CBTC) convened a glioma pathology board, comprising both veterinarian and …
Ancestry-inclusive dog genomics challenges popular breed stereotypes
Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …
Origins and genetic legacy of prehistoric dogs
Dogs were the first domestic animal, but little is known about their population history and to
what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that …
what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that …
OptM: estimating the optimal number of migration edges on population trees using Treemix
RR Fitak - Biology Methods and Protocols, 2021 - academic.oup.com
The software Treemix has become extensively used to estimate the number of migration
events, or edges (m), on population trees from genome-wide allele frequency data …
events, or edges (m), on population trees from genome-wide allele frequency data …
Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology
J Plassais, J Kim, BW Davis, DM Karyadi… - Nature …, 2019 - nature.com
Domestic dog breeds are characterized by an unrivaled diversity of morphologic traits and
breed-associated behaviors resulting from human selective pressures. To identify the …
breed-associated behaviors resulting from human selective pressures. To identify the …
Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture
Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …
DNA methylation clocks for dogs and humans
DNA methylation profiles have been used to develop biomarkers of aging known as
epigenetic clocks, which predict chronological age with remarkable accuracy and show …
epigenetic clocks, which predict chronological age with remarkable accuracy and show …
The evolutionary history of dogs in the Americas
Dogs were present in the Americas before the arrival of European colonists, but the origin
and fate of these precontact dogs are largely unknown. We sequenced 71 mitochondrial and …
and fate of these precontact dogs are largely unknown. We sequenced 71 mitochondrial and …
Barc: Learning to regress 3d dog shape from images by exploiting breed information
Our goal is to recover the 3D shape and pose of dogs from a single image. This is a
challenging task because dogs exhibit a wide range of shapes and appearances, and are …
challenging task because dogs exhibit a wide range of shapes and appearances, and are …