Molecular genetic analysis of circadian timekeeping in Drosophila

PE Hardin - Advances in genetics, 2011 - Elsevier
A genetic screen for mutants that alter circadian rhythms in Drosophila identified the first
clock gene—the period (per) gene. The per gene is a central player within a transcriptional …

The circadian timekeeping system of Drosophila

PE Hardin - Current biology, 2005 - cell.com
Daily rhythms in behavior, physiology and metabolism are controlled by endogenous
circadian clocks. At the heart of these clocks is a circadian oscillator that keeps circadian …

Essential elements of radical pair magnetosensitivity in Drosophila

AA Bradlaugh, G Fedele, AL Munro, CN Hansen… - Nature, 2023 - nature.com
Many animals use Earth's magnetic field (also known as the geomagnetic field) for
navigation. The favoured mechanism for magnetosensitivity involves a blue-light-activated …

JETLAG Resets the Drosophila Circadian Clock by Promoting Light-Induced Degradation of TIMELESS

K Koh, X Zheng, A Sehgal - Science, 2006 - science.org
Organisms ranging from bacteria to humans synchronize their internal clocks to daily cycles
of light and dark. Photic entrainment of the Drosophila clock is mediated by proteasomal …

Molecular and phylogenetic analyses reveal mammalian-like clockwork in the honey bee (Apis mellifera) and shed new light on the molecular evolution of the …

EB Rubin, Y Shemesh, M Cohen, S Elgavish… - Genome …, 2006 - genome.cshlp.org
The circadian clock of the honey bee is implicated in ecologically relevant complex
behaviors. These include time sensing, time-compensated sun-compass navigation, and …

Cryptochromes define a novel circadian clock mechanism in monarch butterflies that may underlie sun compass navigation

H Zhu, I Sauman, Q Yuan, A Casselman… - PLoS …, 2008 - journals.plos.org
The circadian clock plays a vital role in monarch butterfly (Danaus plexippus) migration by
providing the timing component of time-compensated sun compass orientation, a process …

Light-dependent interactions between the Drosophila circadian clock factors cryptochrome, jetlag, and timeless

N Peschel, KF Chen, G Szabo, R Stanewsky - Current biology, 2009 - cell.com
Circadian clocks regulate daily fluctuations of many physiological and behavioral aspects in
life. They are synchronized with the environment via light or temperature cycles [1]. Natural …

Serotonin modulates circadian entrainment in Drosophila

Q Yuan, F Lin, X Zheng, A Sehgal - Neuron, 2005 - cell.com
Entrainment of the Drosophila circadian clock to light involves the light-induced degradation
of the clock protein timeless (TIM). We show here that this entrainment mechanism is …

Multifarious roles of intrinsic disorder in proteins illustrate its broad impact on plant biology

X Sun, EHA Rikkerink, WT Jones, VN Uversky - The Plant Cell, 2013 - academic.oup.com
Intrinsically disordered proteins (IDPs) are highly abundant in eukaryotic proteomes. Plant
IDPs play critical roles in plant biology and often act as integrators of signals from multiple …

The Drosophila circadian network is a seasonal timer

D Stoleru, P Nawathean, M de la Paz Fernández… - Cell, 2007 - cell.com
Previous work in Drosophila has defined two populations of circadian brain neurons,
morning cells (M-cells) and evening cells (E-cells), both of which keep circadian time and …