An update on diagnostic and prognostic biomarkers for traumatic brain injury

KK Wang, Z Yang, T Zhu, Y Shi… - Expert review of …, 2018 - Taylor & Francis
Introduction: Traumatic brain injury (TBI) is a major worldwide neurological disorder of
epidemic proportions. To date, there are still no FDA-approved therapies to treat any forms …

A decade of DTI in traumatic brain injury: 10 years and 100 articles later

MB Hulkower, DB Poliak… - American Journal …, 2013 - Am Soc Neuroradiology
The past decade has seen an increase in the number of articles reporting the use of DTI to
detect brain abnormalities in patients with traumatic brain injury. DTI is well-suited to the …

White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study

MF Kraus, T Susmaras, BP Caughlin, CJ Walker… - Brain, 2007 - academic.oup.com
Traumatic brain injury (TBI) is a serious public health problem. Even injuries classified as
mild, the most common, can result in persistent neurobehavioural impairment. Diffuse …

Traumatic brain injury as a disorder of brain connectivity

JP Hayes, ED Bigler, M Verfaellie - Journal of the International …, 2016 - cambridge.org
Objectives: Recent advances in neuroimaging methodologies sensitive to axonal injury
have made it possible to assess in vivo the extent of traumatic brain injury (TBI)-related …

Diffusion tensor imaging of acute mild traumatic brain injury in adolescents

EA Wilde, SR McCauley, JV Hunter, ED Bigler, Z Chu… - Neurology, 2008 - AAN Enterprises
Background: Despite normal CT imaging and neurologic functioning, many individuals
report postconcussion symptoms following mild traumatic brain injury (MTBI). This …

Diffuse axonal injury and oxidative stress: a comprehensive review

A Frati, D Cerretani, AI Fiaschi, P Frati, V Gatto… - International journal of …, 2017 - mdpi.com
Traumatic brain injury (TBI) is one of the world's leading causes of morbidity and mortality
among young individuals. TBI applies powerful rotational and translational forces to the …

Longitudinal changes in patients with traumatic brain injury assessed with diffusion-tensor and volumetric imaging

BB Bendlin, ML Ries, M Lazar, AL Alexander… - Neuroimage, 2008 - Elsevier
Traumatic brain injury (TBI) is associated with brain volume loss, but there is little information
on the regional gray matter (GM) and white matter (WM) changes that contribute to overall …

The relationship between delirium duration, white matter integrity, and cognitive impairment in intensive care unit survivors as determined by diffusion tensor imaging …

A Morandi, BP Rogers, ML Gunther, K Merkle… - Critical care …, 2012 - journals.lww.com
Objective: Evidence is emerging that delirium duration is a predictor of long-term cognitive
impairment in intensive care unit survivors. Relationships between 1) delirium duration and …

Diffusion tensor imaging changes following mild, moderate and severe adult traumatic brain injury: a meta-analysis

EJ Wallace, JL Mathias, L Ward - Brain imaging and behavior, 2018 - Springer
Diffusion tensor imaging quantifies the asymmetry (fractional anisotropy; FA) and amount of
water diffusion (mean diffusivity/apparent diffusion coefficient; MD/ADC) and has been used …

Diffusion tensor imaging and white matter lesions at the subacute stage in mild traumatic brain injury with persistent neurobehavioral impairment

A Messé, S Caplain, G Paradot, D Garrigue… - Human brain …, 2011 - Wiley Online Library
Mild traumatic brain injury (mTBI) can induce long‐term behavioral and cognitive disorders.
Although the exact origin of these mTBI‐related disorders is not known, they may be the …