Lung cancer (LC) produces some of the most malignant tumors in the world, with high
morbidity and mortality. Tumor immune microenvironment (TIME), a component of the tumor …

Lung cancer remains the leading cause of cancer-related death worldwide. We identify
DSTYK, a dual serine/threonine and tyrosine non-receptor protein kinase, as a novel …

Pancreatic cancer is a highly aggressive malignant tumor, that is becoming increasingly
common in recent years. Despite advances in intensive treatment modalities including …

Using a model of Lewis lung carcinoma (LLC) in vitro and in vivo, we previously
demonstrated increased antitumor activity in CD8+ T-cells reprogrammed with an MEK …

Background. The tumor microenvironment (TME) of lung adenocarcinoma (LUAD) comprise
various cell types that communicate with each other through ligand‐receptor interactions …

Background: Nivolumab has been shown to improve the overall survival (OS) of patients
with recurrent and metastatic head and neck squamous cell carcinoma (R/M HNSCC) …

Statins are suggested to improve cancer survival by possible anti‐inflammatory effect.
However, it remains unclear if concomitant use of statins could improve the efficacy of …

[ES] La principal hipótesis que se ha establecido para esta tesis doctoral es la búsqueda de
biomarcadores predictores de respuesta o resistencia al tratamiento con inmunoterapia …

Background Lung cancer is one of the highly lethal forms of cancer whose incidence has
worldwide rapidly increased over the past few decades. About 80–85% of all lung cancer …

Background Non-small cell lung cancer with homologous recombination deficiency (HRD)
was revealed to have better response to immunotherapy. Long non-coding RNAs (lncRNAs) …