Optimization of metabolomic data processing using NOREVA
A typical output of a metabolomic experiment is a peak table corresponding to the intensity
of measured signals. Peak table processing, an essential procedure in metabolomics, is …
of measured signals. Peak table processing, an essential procedure in metabolomics, is …
Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic …
Background Quality assurance (QA) and quality control (QC) are two quality management
processes that are integral to the success of metabolomics including their application for the …
processes that are integral to the success of metabolomics including their application for the …
STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2
L Zhang, C Jiang, Y Zhong, K Sun, H Jing, J Song… - Nature Cell …, 2023 - nature.com
Evasion of antitumour immunity is a hallmark of cancer. STING, a putative innate immune
signalling adaptor, has a pivotal role in mounting antitumour immunity by coordinating …
signalling adaptor, has a pivotal role in mounting antitumour immunity by coordinating …
[HTML][HTML] Proteogenomic characterization of endometrial carcinoma
We undertook a comprehensive proteogenomic characterization of 95 prospectively
collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This …
collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This …
Proteogenomic analysis of human colon cancer reveals new therapeutic opportunities
We performed the first proteogenomic study on a prospectively collected colon cancer
cohort. Comparative proteomic and phosphoproteomic analysis of paired tumor and normal …
cohort. Comparative proteomic and phosphoproteomic analysis of paired tumor and normal …
MetaboAnalystR 2.0: from raw spectra to biological insights
Global metabolomics based on high-resolution liquid chromatography mass spectrometry
(LC-MS) has been increasingly employed in recent large-scale multi-omics studies …
(LC-MS) has been increasingly employed in recent large-scale multi-omics studies …
NOREVA: enhanced normalization and evaluation of time-course and multi-class metabolomic data
Biological processes (like microbial growth & physiological response) are usually dynamic
and require the monitoring of metabolic variation at different time-points. Moreover, there is …
and require the monitoring of metabolic variation at different time-points. Moreover, there is …
Metabolomic analyses reveal new stage-specific features of COVID-19
H Jia, C Liu, D Li, Q Huang, D Liu… - European …, 2022 - Eur Respiratory Soc
The current pandemic of coronavirus disease 2019 (COVID-19) has affected> 160 million
individuals to date, and has caused millions of deaths worldwide, at least in part due to the …
individuals to date, and has caused millions of deaths worldwide, at least in part due to the …
The N6-methyladenosine METTL3 regulates tumorigenesis and glycolysis by mediating m6A methylation of the tumor suppressor LATS1 in breast cancer
Y Xu, M Song, Z Hong, W Chen, Q Zhang… - Journal of Experimental …, 2023 - Springer
Background Posttranscriptional modification of tumor-associated factors plays a pivotal role
in breast cancer progression. However, the underlying mechanism remains unknown. M6A …
in breast cancer progression. However, the underlying mechanism remains unknown. M6A …
The trans-omics landscape of COVID-19
P Wu, D Chen, W Ding, P Wu, H Hou, Y Bai… - Nature …, 2021 - nature.com
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency.
Various omics results have been reported for COVID-19, but the molecular hallmarks of …
Various omics results have been reported for COVID-19, but the molecular hallmarks of …