Novel approaches to enable equitable access to monoclonal antibodies in low-and middle-income countries

S Malhotra, AI Cameron, D Gotham… - PLOS Global Public …, 2024 - journals.plos.org
Monoclonal antibodies (mAbs) are revolutionizing management of non-communicable
diseases in high-income countries and are increasingly being advanced for a range of …

The Quest for Transformative Tools to Eradicate Malaria

T Mundel - New England Journal of Medicine, 2024 - Mass Medical Soc
We in the global malaria community are at a critical juncture in our journey toward malaria
eradication. Decades of experience in deploying our existing interventions have made it …

Monoclonal Antibodies: Purification, Application in Conventional Methods and Cutting Edge Technology

N Malhotra, A Chahal, A Jain, P Sharma… - Biomedical Materials & …, 2024 - Springer
Antibodies play an important role in health areas such as diagnostic, therapeutic,
vaccination, and prevention. Antibodies were explored by various researchers for various …

How can we get malaria control back on track?

AA El-Moamly - bmj, 2024 - bmj.com
Malaria remains a significant global health burden. The World Health Organization's 2023
malaria report estimates that the number of cases worldwide increased by five million …

Somatic hypermutation-mediated paratope flexibility improves the cross-reactivity of human malaria antibodies

R Murugan, A Hanke, OE Oludada, G Costa… - bioRxiv, 2024 - biorxiv.org
The protective capacity of antibodies targeting circumsporozoite protein on sporozoites of
the malaria parasite Plasmodium falciparum (PfCSP) is linked to high affinity and cross …

Phenotype and function of IL-10 producing NK cells in individuals with malaria experience.

SA McNitt, JK Dick, M Hernandez Castaneda… - bioRxiv, 2024 - biorxiv.org
Plasmodium falciparum infection can trigger high levels of inflammation that lead to fever
and sometimes severe disease. People living in malaria-endemic areas gradually develop …

[HTML][HTML] Global Stability Analysis of the Mathematical Model for Malaria Transmission between Vector and Host Population

RS Alsulami, AA Almatrafi, NA Almohammadi… - American Journal of …, 2024 - scirp.org
In this paper, we discuss a mathematical model of malaria transmission between vector and
host population. We study the basic qualitative properties of the model, the boundedness …

Investigating the Mechanisms Underlying Antibody-Mediated Effector Functions in Malaria and Multisystem Inflammatory Syndrome in Children (MIS-C)

JK Dick - 2024 - search.proquest.com
Antibodies have multiple functions within the body to provide host protection, including
interacting with Fc receptors on innate immune cells to destroy pathogens or cells infected …

[HTML][HTML] Un anticorps monoclonal pour prévenir le paludisme

PD Baudon - jim.fr
Le paludisme est la première endémie parasitaire mondiale. La région Afrique de l'OMS
comprend à elle seule 94% des cas; les infections dues à l'espèce Plasmodium falciparum …