Tissue engineering is a promising and revolutionary strategy to treat patients who suffer the
loss or failure of an organ or tissue, with the aim to restore the dysfunctional tissues and …

Osteoarthritis (OA) is a disabling condition that affects billions of people worldwide and
places a considerable burden on patients and on society owing to its prevalence and …

The regeneration of 3D tissue constructs with clinically relevant sizes, structures, and
hierarchical organizations for translational tissue engineering remains challenging. 3D …

Osteochondral regeneration remains a great challenge due to the limited self‐healing ability
and the complexity of its hierarchical structure and composition. Mg2+ and hypoxia are two …

The development of biomaterials, stem cells and bioactive factors has led to cartilage tissue
engineering becoming a promising tactic to repair cartilage defects. Various polymer three …

Advanced biomaterial‐guided delivery of gene vectors is an emerging and highly attractive
therapeutic solution for targeted articular cartilage repair, allowing for a controlled and …

Articular cartilage injury is a frequent worldwide disease, while effective treatment is urgently
needed. Due to lack of blood vessels and nerves, the ability of cartilage to self-repair is …

Articular cartilage (AC) is an avascular and flexible connective tissue located on the bone
surface in the diarthrodial joints. AC defects are common in the knees of young and …

Hydrogel systems have been widely used to engineer biomimetic niches that capture
microenvironments cues to steer cell fate; however, challenges remain in inducing …

The regeneration of focal articular cartilage defects is complicated by the reduced quality of
the repair tissue and the potential development of perifocal osteoarthritis (OA). Biomaterial …