Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery
A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …
[HTML][HTML] Non-coding RNAs: The potential biomarker or therapeutic target in hepatic ischemia-reperfusion injury
JL Shao, LJ Wang, J Xiao, JF Yang - World Journal of …, 2023 - ncbi.nlm.nih.gov
Hepatic ischemia-reperfusion injury (HIRI) is the major complication of liver surgery and liver
transplantation, that may increase the postoperative morbidity, mortality, tumor progression …
transplantation, that may increase the postoperative morbidity, mortality, tumor progression …
A mitochondria-targeted H2S-activatable fluorogenic probe for tracking hepatic ischemia-reperfusion injury
B Fang, J Yang, L Wang, H Li, J Guo, J Zhang… - Chinese Chemical …, 2024 - Elsevier
Hepatic ischemia-reperfusion injury (HIRI) is the cause of postoperative hepatic dysfunction
and failure, and even death. As an important biological effector molecule, hydrogen sulfide …
and failure, and even death. As an important biological effector molecule, hydrogen sulfide …
TLR4 signalling in ischemia/reperfusion injury: a promising target for linking inflammation, oxidative stress and programmed cell death to improve organ …
S Wang, K Zhang, Q Huang, F Meng… - Frontiers in …, 2024 - frontiersin.org
Transplantations represent the principal therapeutic interventions for terminal organ failure,
a procedure that has salvaged myriad lives annually. Ischemia/reperfusion injury (IRI) is …
a procedure that has salvaged myriad lives annually. Ischemia/reperfusion injury (IRI) is …
A novel fluorescence probe for simultaneous detection of mitochondrial viscosity in hepatic ischemia reperfusion injury models
X Chen, Z Jiang, Z Wang, F He, M Fu, Z Xie, JF Hu - RSC advances, 2024 - pubs.rsc.org
Acute liver failure caused by hepatic ischemia reperfusion injury (HIRI) poses a severe
threat to life, emphasizing the urgent need for precise and timely early diagnosis. Viscosity, a …
threat to life, emphasizing the urgent need for precise and timely early diagnosis. Viscosity, a …
Normothermic Ex Vivo Liver Machine Perfusion in Mouse
H Chen, O Dirsch, M Albadry, PH Ana… - JoVE (Journal of …, 2023 - jove.com
This protocol presents an optimized erythrocytes-free NEVLP system using mouse livers. Ex
vivo preservation of mouse livers was achieved by employing modified cannulas and …
vivo preservation of mouse livers was achieved by employing modified cannulas and …
Icaritin attenuates ischemia–reperfusion injury by anti-inflammation, anti-oxidative stress, and anti-autophagy in mouse liver
Q Sun, R Yang, S Li, H Wang, D Kong, W Zhang… - International …, 2024 - Elsevier
Background Hepatic ischemia–reperfusion (IR) injury is a major complication of liver
transplantation and gravely affects patient prognosis. Icaritin (ICT), the primary plasma …
transplantation and gravely affects patient prognosis. Icaritin (ICT), the primary plasma …
Programmed Cell Death, From Liver Ischemia–Reperfusion Injury Perspective: An Overview
S Luo, R Luo, G Deng, F Huang, Z Lei - Heliyon, 2024 - cell.com
Liver ischemia-reperfusion injury (LIRI) can occur during liver resection, liver transplantation,
shock, and other hemorrhagic conditions, resulting in profound local and systemic effects via …
shock, and other hemorrhagic conditions, resulting in profound local and systemic effects via …
The janus face of serotonin: Regenerative promoter and chronic liver disease aggravator
B Mao, S Liu, S Zhu, F Wu, W Yuan, Y Yan, B Wang - Heliyon, 2024 - cell.com
The progression of liver diseases, from viral hepatitis and fatty liver disease to cirrhosis and
hepatocellular carcinoma (HCC), is the most representative series of pathological events in …
hepatocellular carcinoma (HCC), is the most representative series of pathological events in …
Activation of AMPK/mTOR-Driven Autophagy and Suppression of the HMGB1/TLR4 Pathway with Pentoxifylline Attenuates Doxorubicin-Induced Hepatic Injury in Rats
HH Arab, AH Eid, SE Alsufyani, AM Ashour… - Pharmaceuticals, 2024 - mdpi.com
Despite being an effective chemotherapeutic agent, the clinical use of doxorubicin (DOX) is
limited by several organ toxicities including hepatic injury. Pentoxifylline (PTX) is a …
limited by several organ toxicities including hepatic injury. Pentoxifylline (PTX) is a …