The primary immunodeficiency diseases (PIDs) include many genetic disorders that affect
different components of the innate and adaptive responses. The number of distinct genetic …

Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by
hypogammaglobulinemia and increased susceptibility to recurrent bacterial infections. It is …

Childhood asthma remains a multifactorial disease with heterogeneous clinical phenotype
and complex genetic inheritance. The primary aim of asthma management is to achieve …

Human primary immunodeficiency diseases (PIDs) represent a heterogeneous group of
more than 350 disorders. They are rare diseases, but their global incidence is more relevant …

Background Inborn errors of immunity (IEIs) are considered significant challenges for
children with IEIs, their families, and their medical providers. Infections are the most common …

Bronchiectasis is a condition that has been increasingly diagnosed by chest HRCT. In the
literature, bronchiectasis is divided into bronchiectasis secondary to cystic fibrosis and …

Inborn errors of immunity (IEI) comprise a group of about 490 genetic disorders that lead to
aberrant functioning or the development of distinct immune system components. So far, a …

Background Pneumonia is a major healthcare problem. Rapid pathogen identification is
critical, but often delayed due to the duration of culturing. Early, broad antibacterial therapy …

Background Clear cell renal cell carcinoma (ccRCC) is the most common pathological
subtype of renal cell carcinoma. Bioinformatics analyses were used to screen candidate …

Purpose Pulmonary manifestations are common in patients with primary immunodeficiency
disorders (PIDs) but the prevalence, specific diseases, and their patterns are not well …