The predominant mechanism for resistance to-lactam antibiotics in gram-negative bacteria is
the synthesis of-lactamase. To meet this challenge,-lactams with greater-lactamase stability …

This review examines deoxyadenosylcobalamin (Ado-B12) biosynthesis, transport, use, and
uneven distribution among living forms. We describe how genetic analysis of enteric …

Ions are not traditionally thought to act as first messengers in signal transduction cascades.
However, while searching for genes regulated by the PhoP/PhoQ virulence regulatory …

We have identified a region unique to the Salmonella typhimurium chromosome that is
essential for virulence in mice. This region harbors at least three genes: two (spiA and spiB) …

Mapping the insertion points of 16 signature-tagged transposon mutants on the Salmonella
typhimurium chromosome led to the identification of a 40-kb virulence gene cluster at minute …

The O-antigen is an important component of the outer membrane of Gram-negative bacteria.
It is a repeat unit polysaccharide and consists of a number of repeats of an oligosaccharide …

Salmonella typhimurium causes enteric and systemic disease by invading the intestinal
epithelium of the distal ileum, a process requiring the invasion genes of Salmonella …

Mouse-virulent Salmonella typhimurium strains SR-11 and ATCC 14028-1s express curli
fibers, thin aggregative fibers, at ambient temperature on plates as judged by Western blot …

A model is presented whereby the formation of gene clusters in bacteria is mediated by
transfer of DNA within and among taxa. Bacterial operons are typically composed of genes …

Salmonella is one of the most extensively characterized bacterial pathogens and is a
leading cause of bacterial gastroenteritis. Despite this, we are only just beginning to …