Co‐ordinate regulation of Salmonella typhimurium invasion genes by environmental and regulatory factors is mediated by control of hilA expression

V Bajaj, RL Lucas, C Hwang, CA Lee - Molecular microbiology, 1996 - Wiley Online Library
During infection of their hosts, salmonellae enter intestinal epithelial cells. It has been
proposed that when Salmonellatyphimurium is present in the intestinal lumen, several …

[HTML][HTML] A signal transduction system that responds to extracellular iron

MMSM Wösten, LFF Kox, S Chamnongpol, FC Soncini… - Cell, 2000 - cell.com
Iron is essential for all organisms but can be toxic in excess. Iron homeostasis is typically
regulated by cytoplasmic iron binding proteins, but here we describe a signal transduction …

How Salmonella became a pathogen

EA Groisman, H Ochman - Trends in microbiology, 1997 - cell.com
In many pathogens, virulence can be conferred by a single region of the genome. In
contrast, the facultative intracellular lifestyle of Salmonella demands a large number of …

[HTML][HTML] The Salmonella selC locus contains a pathogenicity island mediating intramacrophage survival

AB Blanc‐Potard, EA Groisman - The EMBO journal, 1997 - embopress.org
Pathogenicity islands are chromosomal clusters of horizontally acquired virulence genes
that are often found at tRNA loci. The selC tRNA locus of Escherichia coli has served as the …

The genetic basis of tetrathionate respiration in Salmonella typhimurium

M Hensel, AP Hinsley, T Nikolaus… - Molecular …, 1999 - Wiley Online Library
A range of bacteria are able to use tetrathionate as a terminal respiratory electron acceptor.
Here we report the identification and characterization of the ttrRSBCA locus required for …

Molecular basis of the magnesium deprivation response in Salmonella typhimurium: identification of PhoP-regulated genes

FC Soncini, E García Véscovi, F Solomon… - Journal of …, 1996 - Am Soc Microbiol
The PhoP-PhoQ two-component system is essential for virulence in Salmonella
typhimurium. This system controls expression of some 40 different proteins, yet most PhoP …

Regulation of polymyxin resistance and adaptation to low-Mg2+ environments

EA Groisman, J Kayser, FC Soncini - Journal of bacteriology, 1997 - Am Soc Microbiol
The PmrA-PmrB two-component system of Salmonella typhimurium controls resistance to
the peptide antibiotic polymyxin B and to several antimicrobial proteins from human …

Applications for green fluorescent protein (GFP) in the study of hostpathogen interactions

RH Valdivia, AE Hromockyj, D Monack… - Gene, 1996 - Elsevier
The green fluorescent protein (GFP) from Aequorea victoria is a novel fluorescent marker
that has potential use in the study of bacterial pathogenicity. To explore some of the potential …

[HTML][HTML] A small protein that mediates the activation of a two‐component system by another two‐component system

LFF Kox, MMSM Wösten, EA Groisman - The EMBO journal, 2000 - embopress.org
Abstract The PmrA–PmrB two‐component system of Salmonella enterica controls resistance
to the peptide antibiotic polymyxin B and to several antimicrobial proteins from human …

Characterization of the O‐antigen gene clusters of Yersinia pseudotuberculosis and the cryptic O‐antigen gene cluster of Yersinia pestis shows that the plague bacillus is most …

M Skurnik, A Peippo, E Ervelä - Molecular microbiology, 2000 - Wiley Online Library
One of the most virulent and feared bacterial pathogens is Yersinia pestis, the aetiologic
agent of bubonic plague. Characterization of the O‐antigen gene clusters of 21 serotypes of …