Introduction: Protein kinases are involved in various cellular functions. About 2% of the
human genome encodes for protein kinases. Dysregulation of protein kinases is implicated …

Purpose The impact of a personalized cancer treatment strategy (ie, matching patients with
drugs based on specific biomarkers) is still a matter of debate. Methods We reviewed phase …

Liquid droplet has emerged as a flexible intracellular compartment that modulates various
cellular processes. Here, we uncover an antimetastatic mechanism governed by the liquid …

Severe side effects and poor therapeutic efficacy are the main drawbacks of current
anticancer drugs. These problems can be mitigated by targeting, but the targeting efficacy of …

Anticancer drug gefitinib causes inflammation-based side effects, such as interstitial
pneumonitis. However, its mechanisms remain unknown. Here, we provide evidence that …

Despite intensive surgical excision, radiation therapy, and chemotherapy, the current life
expectancy for patients diagnosed with glioblastoma multiforme is only 12 to 15 months …

Intratumoral heterogeneity is a substantial cause of drug resistance development during
chemotherapy or other drug treatments for cancer. Therefore, monitoring and measuring cell …

Statement of Retraction We, the Editors and Publisher of the journal Cell Cycle, have
retracted the following article: Xuehao Li, Xin Zhang, Chunlu Yang, Sui Cui, Qiming Shen …

Objective The present work was aimed to develop gefitinib solid lipid nanoparticles (GFT-
SLN) using novel lipids (Lipoid S PC-3) and to analyse its cell cytotoxicity and tissue …

Targeting the epidermal growth factor receptor (EGFR) is an alternative therapeutic strategy
for the treatment of triple-negative breast cancer (TNBC). Here, we designed EGFR-targeting …