The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030

B Vogel, M Acevedo, Y Appelman, CNB Merz… - The Lancet, 2021 - thelancet.com
Cardiovascular disease is the leading cause of death in women. Decades of grassroots
campaigns have helped to raise awareness about the impact of cardiovascular disease in …

Obesity and cardiovascular disease: a scientific statement from the American Heart Association

TM Powell-Wiley, P Poirier, LE Burke, JP Després… - Circulation, 2021 - Am Heart Assoc
The global obesity epidemic is well established, with increases in obesity prevalence for
most countries since the 1980s. Obesity contributes directly to incident cardiovascular risk …

Coronary Microvascular Dysfunction Across the Spectrum of Cardiovascular Diseases: JACC State-of-the-Art Review

MG Del Buono, RA Montone, M Camilli… - Journal of the American …, 2021 - jacc.org
Coronary microvascular dysfunction (CMD) encompasses several pathogenetic
mechanisms involving coronary microcirculation and plays a major role in determining …

Obesity phenotypes, diabetes, and cardiovascular diseases

ME Piché, A Tchernof, JP Després - Circulation research, 2020 - Am Heart Assoc
This review addresses the interplay between obesity, type 2 diabetes mellitus, and
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …

Coronary microvascular dysfunction

F Vancheri, G Longo, S Vancheri, M Henein - Journal of Clinical …, 2020 - mdpi.com
Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …

Microvascular dysfunction in diabetes mellitus and cardiometabolic disease

WB Horton, EJ Barrett - Endocrine reviews, 2021 - academic.oup.com
This review takes an inclusive approach to microvascular dysfunction in diabetes mellitus
and cardiometabolic disease. In virtually every organ, dynamic interactions between the …

Myocardial interstitial fibrosis in heart failure: biological and translational perspectives

A González, EB Schelbert, J Díez, J Butler - Journal of the American …, 2018 - jacc.org
Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the
development of heart failure. Basic research has provided abundant evidence for the …

Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance

D Sun, J Wang, S Toan, D Muid, R Li, X Chang, H Zhou - Angiogenesis, 2022 - Springer
Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes,
and can accelerate diabetes-related microvascular and macrovascular complications by …

Screening of potential cardiac involvement in competitive athletes recovering from COVID-19: an expert consensus statement

D Phelan, JH Kim, MD Elliott, MM Wasfy, P Cremer… - Cardiovascular …, 2020 - jacc.org
As our understanding of the complications of coronavirus disease-2019 (COVID-19) evolve,
subclinical cardiac pathology such as myocarditis, pericarditis, and right ventricular …

Deep learning of the retina enables phenome-and genome-wide analyses of the microvasculature

SM Zekavat, VK Raghu, M Trinder, Y Ye, S Koyama… - Circulation, 2022 - Am Heart Assoc
Background: The microvasculature, the smallest blood vessels in the body, has key roles in
maintenance of organ health and tumorigenesis. The retinal fundus is a window for human …