Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

Abstract N 6-methyladenosine (m6A) is the most abundant epigenetic modification of RNA,
and its dysregulation drives aberrant transcription and translation programs that promote …

Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …

T cells genetically engineered to express chimeric antigen receptors (CARs) have proven—
and impressive—therapeutic activity in patients with certain subtypes of B cell leukaemia or …

Natural killer (NK) cells are unique immune effectors able to kill cancer cells by direct
recognition of surface ligands, without prior sensitization. Allogeneic NK transfer is a highly …

Nitric oxide and its production by iNOS is an established mechanism critical to tumor
promotion or suppression. Macrophages have important roles in immunity, development …

Natural killer (NK) cells are a population of innate lymphoid cells playing a pivotal role in
host immune responses against infection and tumor growth. These cells have a powerful …

Breast cancer progression is a complex process controlled by genetic and epigenetic factors
that coordinate the crosstalk between tumor cells and the components of tumor …

Simple Summary In this review, we describe arginine's role as a signaling metabolite,
epigenetic regulator and mitochondrial modulator in cancer cells, and summarize recent …

Cells of the innate immunity play an important role in tumor immunotherapy. Thus, NK cells
can control tumor growth and metastatic spread. Thanks to their strong cytolytic activity …