[HTML][HTML] The presynaptic active zone
TC Südhof - Neuron, 2012 - cell.com
Neurotransmitters are released by synaptic vesicle exocytosis at the active zone of a
presynaptic nerve terminal. In this review, I discuss the molecular composition and function …
presynaptic nerve terminal. In this review, I discuss the molecular composition and function …
Protein tyrosine phosphatases PTPδ, PTPσ, and LAR: presynaptic hubs for synapse organization
H Takahashi, AM Craig - Trends in neurosciences, 2013 - cell.com
Synapse development requires differentiation of presynaptic neurotransmitter release sites
and postsynaptic receptive apparatus coordinated by synapse organizing proteins. In …
and postsynaptic receptive apparatus coordinated by synapse organizing proteins. In …
m6A modulates neuronal functions and sex determination in Drosophila
Abstract N 6-methyladenosine RNA (m6A) is a prevalent messenger RNA modification in
vertebrates. Although its functions in the regulation of post-transcriptional gene expression …
vertebrates. Although its functions in the regulation of post-transcriptional gene expression …
[HTML][HTML] RNA localization is a key determinant of neurite-enriched proteome
A Zappulo, D Van Den Bruck, C Ciolli Mattioli… - Nature …, 2017 - nature.com
Protein subcellular localization is fundamental to the establishment of the body axis, cell
migration, synaptic plasticity, and a vast range of other biological processes. Protein …
migration, synaptic plasticity, and a vast range of other biological processes. Protein …
LAR-RPTPs: synaptic adhesion molecules that shape synapse development
The synapse is the most elementary operating unit in neurons, creating neural circuits that
underlie all brain functions. Synaptic adhesion molecules initiate neuronal synapse …
underlie all brain functions. Synaptic adhesion molecules initiate neuronal synapse …
[HTML][HTML] Synapse development and maturation at the drosophila neuromuscular junction
VT Chou, SA Johnson, D Van Vactor - Neural development, 2020 - Springer
Synapses are the sites of neuron-to-neuron communication and form the basis of the neural
circuits that underlie all animal cognition and behavior. Chemical synapses are specialized …
circuits that underlie all animal cognition and behavior. Chemical synapses are specialized …
A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3
MS Paul, SL Michener, H Pan, H Chan… - The American Journal of …, 2024 - cell.com
PPFIA3 encodes the protein-tyrosine phosphatase, receptor-type, F-polypeptide-interacting-
protein-alpha-3 (PPFIA3), which is a member of the LAR-protein-tyrosine phosphatase …
protein-alpha-3 (PPFIA3), which is a member of the LAR-protein-tyrosine phosphatase …
Molecular organization and plasticity of the cytomatrix at the active zone
ED Gundelfinger, A Fejtova - Current opinion in neurobiology, 2012 - Elsevier
Regulated neurotransmitter release from presynaptic boutons is crucial for the functioning of
chemical synapses, what in turn governs the functional performance of the nervous system …
chemical synapses, what in turn governs the functional performance of the nervous system …
Cellular and molecular mechanisms underlying presynapse formation
PH Chia, P Li, K Shen - Journal of Cell Biology, 2013 - rupress.org
Synapse formation is a highly regulated process that requires the coordination of many cell
biological events. Decades of research have identified a long list of molecular components …
biological events. Decades of research have identified a long list of molecular components …
Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission
SA Spangler, SK Schmitz, JT Kevenaar… - Journal of Cell …, 2013 - rupress.org
The presynaptic active zone mediates synaptic vesicle exocytosis, and modulation of its
molecular composition is important for many types of synaptic plasticity. Here, we identify …
molecular composition is important for many types of synaptic plasticity. Here, we identify …