Therapeutic drug monitoring (TDM) and model‐informed precision dosing (MIPD) have
evolved as important tools to inform rational dosing of antibiotics in individual patients with …

Precision medicine requires individualized modeling of disease and drug dynamics, with
machine learning-based computational techniques gaining increasing popularity. The …

Background Intravenous pharmacokinetics and oral bioavailability of cannabidiol (CBD) with
different formulations have not been investigated in horses and may represent a starting …

Background Busulfan is commonly used in the chemotherapy prior to hematopoietic cell
transplantation (HCT). Busulfan has a narrow therapeutic window and a well-established …

Aims Linezolid is often used for the infections caused by drug‐resistant Gram‐positive
bacteria. Recent studies suggest that large between‐subject variability (BSV) and within …

Prior to his passing, Dr. Roger Jelliffe, expressed the need for educating future physicians
and clinical pharmacists on the availability of computer-based tools to support dose …

Population pharmacokinetics consists of analyzing pharmacokinetic (PK) data collected in
groups of individuals. Population PK is widely used to guide drug development and to inform …

To combat the rise of multidrug-resistant microorganisms like methicillin-resistant
Staphylococcus aureus (MRSA), new antibiotic classes are required. Hence, experimental …

Daptomycin is a candidate for therapeutic drug monitoring (TDM). The objectives of this work
were to implement and compare two pharmacometric tools for daptomycin TDM and …

Pharmacokinetics (PK) is a branch of pharmacology present and of vital importance for the
research and development (R&D) of new drugs, post-market monitoring, and continued …