Role of lipoprotein (a) in atherosclerotic cardiovascular disease: A review of current and emerging therapies
Abstract Lipoprotein (a), or Lp (a), is structurally like low‐density lipoprotein (LDL) but differs
in that it contains glycoprotein apolipoprotein (a)[apo (a)]. Due to its prothrombotic and …
in that it contains glycoprotein apolipoprotein (a)[apo (a)]. Due to its prothrombotic and …
The relationship between lipoprotein (a) and risk of cardiovascular disease: a Mendelian randomization analysis
S Wang, L Zha, J Chen, D Du, D Liu, M Zhong… - European Journal of …, 2022 - Springer
Abstract Background Lipoprotein (a)[Lp (a)] is one of the residual risk factors for
cardiovascular disease (CVD) in the setting of optimal low-density lipoprotein cholesterol …
cardiovascular disease (CVD) in the setting of optimal low-density lipoprotein cholesterol …
Lipoprotein (a): a genetically determined risk factor for Cardiovascular disease
SM Marcovina - Critical Reviews in Clinical Laboratory Sciences, 2023 - Taylor & Francis
Lipoprotein (a) is a complex lipoprotein with unique characteristics distinguishing it from all
the other apolipoprotein B-containing lipoprotein particles. Its lipid composition and the …
the other apolipoprotein B-containing lipoprotein particles. Its lipid composition and the …
Lipoprotein (a): evidence for role as a causal risk factor in cardiovascular disease and emerging therapies
HS Bhatia, MJ Wilkinson - Journal of clinical medicine, 2022 - mdpi.com
Lipoprotein (a)(Lp (a)) is an established risk factor for multiple cardiovascular diseases.
Several lines of evidence including mechanistic, epidemiologic, and genetic studies support …
Several lines of evidence including mechanistic, epidemiologic, and genetic studies support …
Atherosclerotic plaque stabilization and regression: a review of clinical evidence
A Sarraju, SE Nissen - Nature Reviews Cardiology, 2024 - nature.com
Atherosclerotic plaque results from a complex interplay between lipid deposition,
inflammatory changes, cell migration and arterial wall injury. Over the past two decades …
inflammatory changes, cell migration and arterial wall injury. Over the past two decades …
[HTML][HTML] The promise of PCSK9 and lipoprotein (a) as targets for gene silencing therapies
DC Chan, GF Watts - Clinical Therapeutics, 2023 - Elsevier
Purpose High plasma concentrations of LDL and lipoprotein (a)(Lp [a]) are independent and
causal risk factors for atherosclerotic cardiovascular disease (ASCVD). There is an unmet …
causal risk factors for atherosclerotic cardiovascular disease (ASCVD). There is an unmet …
[HTML][HTML] Non-genetic influences on lipoprotein (a) concentrations
B Enkhmaa, L Berglund - Atherosclerosis, 2022 - Elsevier
An elevated level of lipoprotein (a)[Lp (a)] is a genetically regulated, independent, causal
risk factor for cardiovascular disease. However, the extensive variability in Lp (a) levels …
risk factor for cardiovascular disease. However, the extensive variability in Lp (a) levels …
Current biomarkers for carotid artery stenosis: a comprehensive review of the literature
H Khan, F Shaikh, MH Syed, M Mamdani, G Saposnik… - Metabolites, 2023 - mdpi.com
Carotid artery stenosis (CAS), an atherosclerotic disease of the carotid artery, is one of the
leading causes of transient ischemic attacks (TIA) and cerebrovascular attacks (CVA). The …
leading causes of transient ischemic attacks (TIA) and cerebrovascular attacks (CVA). The …
Associations of homeostatic model assessment for insulin resistance trajectories with cardiovascular disease incidence and mortality
Background: Whether trends in insulin resistance changes are related to the risk of
cardiovascular disease (CVD) incidence and mortality remains unclear. We aimed to …
cardiovascular disease (CVD) incidence and mortality remains unclear. We aimed to …
Lipoprotein (a) as a risk factor for cardiovascular diseases: pathophysiology and treatment perspectives
P Vinci, FG Di Girolamo, E Panizon, LM Tosoni… - International journal of …, 2023 - mdpi.com
Cardiovascular disease (CVD) is still a leading cause of morbidity and mortality, despite all
the progress achieved as regards to both prevention and treatment. Having high levels of …
the progress achieved as regards to both prevention and treatment. Having high levels of …