The role of DNA damage repair (DDR) system in response to immune checkpoint inhibitor (ICI) therapy
As our understanding of the mechanisms of cancer treatment has increased, a growing
number of studies demonstrate pathways through which DNA damage repair (DDR) affects …
number of studies demonstrate pathways through which DNA damage repair (DDR) affects …
Therapeutic strategies to enhance tumor antigenicity: making the tumor detectable by the immune system
D Meraviglia-Crivelli, A Zheleva, M Barainka, B Moreno… - Biomedicines, 2022 - mdpi.com
Cancer immunotherapy has revolutionized the oncology field, but many patients still do not
respond to current immunotherapy approaches. One of the main challenges in broadening …
respond to current immunotherapy approaches. One of the main challenges in broadening …
Apigeninidin-enriched Sorghum bicolor (L. Moench) extracts alleviate Aflatoxin B1-induced dysregulation of male rat hypothalamic-reproductive axis
We examined the protective effect of the apigeninidin (API)-enriched fraction from Sorghum
bicolor sheaths extracts (SBE-05, SBE-06, and SBE-07) against aflatoxin B1 (AFB1)-induced …
bicolor sheaths extracts (SBE-05, SBE-06, and SBE-07) against aflatoxin B1 (AFB1)-induced …
[HTML][HTML] Contribution of common plastic-related endocrine disruptors to epithelial-mesenchymal transition (EMT) and tumor progression
M Pesonen, K Vähäkangas - Chemosphere, 2022 - Elsevier
Many chemicals, including many endocrine disruptors (EDCs) are known to leach out from
various plastic consumer products and waste, and are widespread in the environment …
various plastic consumer products and waste, and are widespread in the environment …
[PDF][PDF] Mechanistic insight into the bioactivity of prodigiosin-entrapped lipid nanoparticles against triple-negative breast, lung and colon cancer cell lines
TH Gugu, CO Eze, FC Kenechukwu, MAKM Bintang… - Heliyon, 2023 - cell.com
This research investigates the potentials of prodigiosin (PG) derived from bacteria and its
formulations against triple-negative breast (TNB), lung, and colon cancer cells. The PG was …
formulations against triple-negative breast (TNB), lung, and colon cancer cells. The PG was …
[HTML][HTML] Case report: malignant melanoma associated with COVID-19: a coincidence or a clue?
AA Leis, AP Montesi, SM Khan, M Montesi - Frontiers in Medicine, 2022 - frontiersin.org
Following SARS-CoV-2 infection in humans, there is upregulation of proinflammatory
molecules S100 calcium binding protein B (S100B), high-mobility group box-1 (HMGB1) …
molecules S100 calcium binding protein B (S100B), high-mobility group box-1 (HMGB1) …
[HTML][HTML] Bacterial immunotherapy: is it a weapon in our arsenal in the fight against cancer?
Advances in understanding the genetic basis of cancer have driven alternative treatment
approaches. Recent findings have demonstrated the potential of bacteria and it's …
approaches. Recent findings have demonstrated the potential of bacteria and it's …
Exposure to polycyclic aromatic hydrocarbons promotes the progression of low‐grade cervical intraepithelial neoplasia: A population‐based cohort study in China
M Cui, L Song, R Mao, Y Lyu, L Ding… - … Journal of Cancer, 2024 - Wiley Online Library
Low‐grade cervical intraepithelial neoplasia (CIN1) is an early stage of cervical cancer
development. Previously, we reported that exposure to polycyclic aromatic hydrocarbons …
development. Previously, we reported that exposure to polycyclic aromatic hydrocarbons …
Antitumor activity of Urtica dioica seed extract on diethylnitrosamine-induced liver carcinogenesis in rats
Hepatocellular carcinoma (HCC) is a significant health problem for human life; therefore,
new therapeutic approaches are essential. In vitrostudies have shown that the extract …
new therapeutic approaches are essential. In vitrostudies have shown that the extract …
Genes and the Environment in Cancer: Focus on Environmentally Induced DNA Methylation Changes
F Coppedè - Cancers, 2023 - mdpi.com
Cancer has traditionally been viewed as a genetic disorder resulting from the accumulation
of gene mutations, chromosomal rearrangements, and aneuploidies in somatic cells …
of gene mutations, chromosomal rearrangements, and aneuploidies in somatic cells …