The feeding of cuprizone (CPZ) to animals has been extensively used to model the
processes of demyelination and remyelination, with many papers adopting a narrative linked …

Sleep-wake disturbances are defined as perceived or actual alterations in sleep that result
in impaired daytime functioning. Unlike other cancers, there is limited information about …

Excessive daytime sleepiness (EDS) and fatigue are some of the most frequent symptoms in
neurological diseases and could impact on quality of life by increasing the risk of accidents …

Sleep disturbances are pervasive in patients with multiple sclerosis (MS), with incidence
about four times higher compared to the general population. The most frequent primary …

Cortisol is the end product of the hypothalamic-pituitary-adrenal (HPA) axis, and its
production is increased mainly in stressful situations or in chronic disorders accompanied by …

Introduction Fatigue and sleep disorders are frequently reported in patients affected by
Multiple Sclerosis (MS) but the causes and the relationship are not yet fully understood. This …

Sleep disturbance is common in people with multiple sclerosis and may worsen fatigue;
however, the assessment of sleep-fatigue relationships varies across studies. To better …

Sleep problems are common in people with multiple sclerosis (MS). Reported prevalence
rates of sleep-disordered breathing (SDB) vary between 0 and 87%. Differences in …

Objectives Restless legs syndrome (RLS) symptoms are common in Multiple Sclerosis (MS)
patients. The aim of the current study was to examine for the first time whether RLS could …

Purpose Studies on hypothalamic changes in patients with relapsing remitting multiple
sclerosis (RRMS) are very scarce, despite the fact that the relationship with the …