Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

TJ Keane, IT Swinehart, SF Badylak - Methods, 2015 - Elsevier
Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …

Decellularized tissue and cell-derived extracellular matrices as scaffolds for orthopaedic tissue engineering

CW Cheng, LD Solorio, E Alsberg - Biotechnology advances, 2014 - Elsevier
The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …

The extracellular matrix as a biologic scaffold material

SF Badylak - Biomaterials, 2007 - Elsevier
Biologic scaffolds composed of naturally occurring extracellular matrix (ECM) have received
significant attention for their potential therapeutic applications. The full potential of the ability …

The extracellular matrix as a scaffold for tissue reconstruction

SF Badylak - Seminars in cell & developmental biology, 2002 - Elsevier
The extracellular matrix (ECM) consists of a complex mixture of structural and functional
proteins and serves an important role in tissue and organ morphogenesis, maintenance of …

Tumor organoid models in precision medicine and investigating cancer-stromal interactions

R Xu, X Zhou, S Wang, C Trinkle - Pharmacology & therapeutics, 2021 - Elsevier
Tumor development and progression require chemical and mechanical cues derived from
cellular and non-cellular components in the tumor microenvironment, including the …

Hydrogels derived from central nervous system extracellular matrix

CJ Medberry, PM Crapo, BF Siu, CA Carruthers… - Biomaterials, 2013 - Elsevier
Biologic scaffolds composed of extracellular matrix (ECM) are commonly used repair
devices in preclinical and clinical settings; however the use of these scaffolds for peripheral …

Biomaterials for tissue engineering

BS Kim, CE Baez, A Atala - World journal of urology, 2000 - Springer
Biomaterials play a critical role in the engineering of new functional genitourinary tissues for
the replacement of lost or malfunctioning tissues. They provide a temporary scaffolding to …

Tissue engineering of human bladder

A Atala - British medical bulletin, 2011 - academic.oup.com
There are a number of conditions of the bladder that can lead to loss of function. Many of
these require reconstructive procedures. However, current techniques may lead to a number …

Composition and biomechanical properties of the bladder acellular matrix graft: comparative analysis in rat, pig and human

Dahms, Piechota, Dahiya, Lue… - British journal of …, 1998 - Wiley Online Library
Objective To compare the composition and mechanical properties of the newly developed
bladder acellular matrix graft (BAMG) with the normal urinary bladder in rat, pig and human …

[图书][B] Scaffolding in tissue engineering

PX Ma, J Elisseeff - 2005 - taylorfrancis.com
The growing interest in scaffolding design and increasing research programs dedicated to
regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While …