Hereditary angioedema is a rare inherited disorder characterized by recurrent episodes of
the accumulation of fluids outside of the blood vessels, causing rapid swelling of tissues in …

Hereditary angioedema with C1 Inhibitor deficiency (C1-INH-HAE) is caused by a
constellation of variants of the SERPING1 gene (n= 809; 1,494 pedigrees), accounting for …

The evolution in the knowledge of rare genetic diseases such as hereditary angioedema
(HAE) has increased at a parallel pace with the development of new molecular tools. The …

Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is a rare and life-
threatening condition characterized by recurrent localized edema. We conducted a …

Biochemical studies performed during the last decades resulted in the development of
various innovative medicinal products for hereditary angioedema (HAE). These therapeutic …

Background There is paucity of literature on long‐term follow‐up of patients with hereditary
angioedema (HAE) from developing countries. Objective This study was carried out to …

Angioedema is a relatively rare but potentially life-threatening adverse reaction to
angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs) …

Understanding pre-mRNA splicing is crucial to accurately diagnosing and treating genetic
diseases. However, mutations that alter splicing can exert highly diverse effects. Of all the …

Background Hereditary angioedema (HAE) is a rare disease characterized by recurrent
attacks of severe swellings of the skin and submucosa. More than 900 variants of the …

Evidence Acquisition: In order to fulfill the objectives of this study, the following databases
were searched: Medline, Scopus, Web of Science, EBSCO, Open Access Journals, and …