[HTML][HTML] Dietary selenium alleviated mouse liver oxidative stress and NAFLD induced by obesity by regulating the KEAP1/NRF2 pathway

Y Wang, B Liu, P Wu, Y Chu, S Gui, Y Zheng, X Chen - Antioxidants, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) occurs when excess fat is stored in the liver and it
is strongly linked with metabolic syndrome and oxidative stress. Selenium (Se) is an …

Mitochondrial glutathione: features, regulation and role in disease

M Marí, A Morales, A Colell, C García-Ruiz… - … et Biophysica Acta (BBA …, 2013 - Elsevier
BACKGROUND: Mitochondria are the powerhouse of mammalian cells and the main source
of reactive oxygen species (ROS) associated with oxygen consumption. In addition, they …

1,25(OH)2D3 Inhibited Ferroptosis in Zebrafish Liver Cells (ZFL) by Regulating Keap1-Nrf2-GPx4 and NF-κB-hepcidin Axis

K Cheng, Y Huang, C Wang - International Journal of Molecular Sciences, 2021 - mdpi.com
Ferroptosis is a kind of iron-dependent programed cell death. Vitamin D has been shown to
be an antioxidant and a regulator of iron metabolism, but the relationship between vitamin D …

Plant glutathione peroxidases: non-heme peroxidases with large functional flexibility as a core component of ROS-processing mechanisms and signalling

K Bela, R Riyazuddin, J Csiszár - Antioxidants, 2022 - mdpi.com
Glutathione peroxidases (GPXs) are non-heme peroxidases catalyzing the reduction of
H2O2 or organic hydroperoxides to water or corresponding alcohols using glutathione …

[HTML][HTML] Oxidized phospholipids: from molecular properties to disease

GO Fruhwirth, A Loidl, A Hermetter - Biochimica et Biophysica Acta (BBA) …, 2007 - Elsevier
Oxidized lipids are generated from (poly) unsaturated diacyl-and alk (en) ylacyl
glycerophospholipids under conditions of oxidative stress. The great variety of reaction …

Regulation of endothelial function by mitochondrial reactive oxygen species

ME Widlansky, DD Gutterman - Antioxidants & redox signaling, 2011 - liebertpub.com
Mitochondria are well known for their central roles in ATP production, calcium homeostasis,
and heme and steroid biosynthesis. However, mitochondrial reactive oxygen species (ROS) …

Seleno‐independent glutathione peroxidases: More than simple antioxidant scavengers

S Herbette, P Roeckel‐Drevet, JR Drevet - The FEBS journal, 2007 - Wiley Online Library
Glutathione peroxidases (GPXs, EC 1.11. 1.9) were first discovered in mammals as key
enzymes involved in scavenging of activated oxygen species (AOS). Their efficient …

The latest view on the mechanism of ferroptosis and its research progress in spinal cord injury

Y Chen, S Liu, J Li, Z Li, J Quan, X Liu… - Oxidative medicine …, 2020 - Wiley Online Library
Ferroptosis is a recently identified nonapoptotic form of cell death whose major markers are
iron dependence and accumulation of lipid reactive oxygen species, accompanied by …

Glutathione/thioredoxin systems modulate mitochondrial H2O2 emission: An experimental-computational study

MA Aon, BA Stanley, V Sivakumaran… - Journal of General …, 2012 - rupress.org
The net emission of hydrogen peroxide (H2O2) from mitochondria results from the balance
between reactive oxygen species (ROS) continuously generated in the respiratory chain and …

CircDTL functions as an oncogene and regulates both apoptosis and ferroptosis in non-small cell lung cancer cells

W Shanshan, M Hongying, F Jingjing, Y Yiming… - Frontiers in …, 2021 - frontiersin.org
Background: Circular RNAs (circRNA) play an essential role in the tumorigenesis of non-
small cell lung cancer (NSCLC). CircDTL is a novel identified circRNA with little information …