[HTML][HTML] Anticancer Activity of Metallodrugs and Metallizing Host Defense Peptides—Current Developments in Structure-Activity Relationship

CMC Andrés, JM Pérez de la Lastra… - International Journal of …, 2024 - mdpi.com
This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …

[HTML][HTML] Reactive oxygen species and its role in pathogenesis and resistance to therapy in acute myeloid leukemia

JS Khorashad, S Rizzo, A Tonks - Cancer Drug Resistance, 2024 - ncbi.nlm.nih.gov
Relapse following a short clinical response to therapy is the major challenge for the
management of acute myeloid leukemia (AML) patients. Leukemic stem cells (LSC), as the …

From Intercalation to External Binding: Ru (II) Complexes with a Spiro Ligand for TAR RNA Selective Binding and HIV-1 Reverse Transcriptase Inhibition

DD Xie, R Song, X Cheng, H Zhang, YF Wei… - Inorganic …, 2024 - ACS Publications
As a typical RNA virus, the genetic information on HIV-1 is entirely stored in RNA. The
reverse transcription activity of HIV-1 reverse transcriptase (RT) plays a crucial role in the …

[HTML][HTML] Ruthenium p-Cymene Complexes Incorporating Substituted Pyridine–Quinoline-Based Ligands: Synthesis, Characterization, and Cytotoxic Properties

A Kokkosi, E Garofallidou, N Zacharopoulos… - Molecules, 2024 - mdpi.com
Organometallic complexes of the formula [Ru (N^ N)(p-cymene) Cl][X](N^ N= bidentate
polypyridyl ligands, p-cymene= 1-methyl-4-(1-methylethyl)-benzene, X= counter anion), are …

Phosphate-Buffered Saline and Dimethyl Sulfoxide Enhance the Antivenom Action of Ruthenium Chloride against Crotalus atrox Venom in Human Plasma—A …

VG Nielsen - International Journal of Molecular Sciences, 2024 - mdpi.com
Ruthenium chloride (RuCl3) is widely utilized for synthesis and catalysis of numerous
compounds in academia and industry and is utilized as a key molecule in a variety of …

Anticancer Activity of Metallodrugs and Metallizing Host Defense Peptides—Current Developments in Structure-Activity Relationship

CM Curieses Andrés, JM Pérez de Lastra… - 2024 - digital.csic.es
This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …

[PDF][PDF] PHАRMACOLOGICAL ACTIVITY OF METAL-BASED ORGANIC COMPLEXES AGAINST DIFFERENT VIRAL DISEASES

DD Tsvetkova, SD Marangozov, I Ivanova - 2024 - pharmacophorejournal.com
Viral diseases are caused by viruses, which by attachment of their capsid proteins to the
receptors of the surface of living cells can penetrate cells through receptor-mediated …

Distinguish G4 Dnas by a Ruthenium (Ii) Complex Coordinated with Cinnamenyl Phenanthroline [1, 10][4, 5 F] Imidazole

S Gao, W Hong, W Deng, J Liang, Q Wu, B Zhai… - Available at SSRN … - papers.ssrn.com
Herein, the distinguish of varied G4 DNAs by ruthenium (II) complex, Ru [(bpy) 2
(CiPIP)](ClO4) 2 (bpy= 2, 2'-bipyridine, CiPIP= cinnamenyl phenanthroline [1, 10][4, 5f] …