Using autopsies to dissect COVID-19 pathogenesis

F Heinrich, KD Mertz, M Glatzel, M Beer… - Nature …, 2023 - nature.com
The emergence of SARS-CoV-2 has resulted in millions of deaths as a result of COVID-19.
Suitable models were missing at the beginning of the pandemic, and studies investigating …

Long COVID-19 pathophysiology: what do we know so far?

NR Tziolos, P Ioannou, S Baliou, DP Kofteridis - Microorganisms, 2023 - mdpi.com
Long COVID-19 is a recognized entity that affects millions of people worldwide. Its broad
clinical symptoms include thrombotic events, brain fog, myocarditis, shortness of breath …

COVID-19 as a Risk Factor for Alzheimer's Disease

M Golzari-Sorkheh, DF Weaver… - Journal of Alzheimer's …, 2023 - content.iospress.com
Severe acute respiratory disease coronavirus 2 (SARS-CoV-2) is responsible for the
coronavirus disease 2019 (COVID-19) pandemic. Although a primarily respiratory disease …

Brain hypoxia, neurocognitive impairment, and quality of life in people post-COVID-19

DD Adingupu, A Soroush, A Hansen, R Twomey… - Journal of …, 2023 - Springer
Objective Systemic hypoxia occurs in COVID-19 infection; however, it is unknown if cerebral
hypoxia occurs in convalescent individuals. We have evidence from other conditions …

Neuropathology and inflammatory cell characterization in 10 autoptic COVID-19 brains

D Colombo, L Falasca, L Marchioni, A Tammaro… - Cells, 2021 - mdpi.com
COVID-19 presents with a wide range of clinical neurological manifestations. It has been
recognized that SARS-CoV-2 infection affects both the central and peripheral nervous …

Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19

JF Fullard, HC Lee, G Voloudakis, S Suo, B Javidfar… - Genome medicine, 2021 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, has been associated with …

Global trends in clinical studies of ivermectin in COVID-19

M Yagisawa, PJ Foster, H Hanaki… - The japanese journal of …, 2021 - jstage.jst.go.jp
Response to the initial alarm bells of the Coronavirus infection, which occurred in Wuhan
City, Hubei Province, China in November 2019, was delayed as it was announced to be a …

Cerebrospinal fluid in COVID-19 neurological complications: Neuroaxonal damage, anti-SARS-Cov2 antibodies but no evidence of cytokine storm

MA Garcia, PV Barreras, A Lewis, G Pinilla… - Journal of the …, 2021 - Elsevier
Objective To study in cerebrospinal fluid (CSF) of COVID-19 subjects if a “cytokine storm” or
neuroinflammation are implicated in pathogenesis of neurological complications. Methods …

Cognitive impairment after long COVID-19: Current evidence and perspectives

Z Li, Z Zhang, Z Zhang, Z Wang, H Li - Frontiers in Neurology, 2023 - frontiersin.org
COVID-19, caused by the SARS-CoV-2 virus, is a respiratory infectious disease. While most
patients recover after treatment, there is growing evidence that COVID-19 may result in …

Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection

M Massimo, C Barelli, C Moreno, C Collesi… - Brain, 2023 - academic.oup.com
Maternal viral infection and immune response are known to increase the risk of altered
development of the foetal brain. Given the ongoing global pandemic of coronavirus disease …