T cells can acquire a broad spectrum of differentiation states following activation. At the
extreme ends of this continuum are short-lived cells equipped with effector machinery and …

With cancer incidence rates continuing to increase and occurrence of resistance in drug
treatment, there is a pressing demand to find safer and more effective anticancer strategy for …

The activity of 5′-adenosine monophosphate-activated protein kinase (AMPK) is inversely
correlated with the cellular availability of glucose. When glucose levels are low, the …

Immunotherapy has achieved revolutionary success in clinics, but it remains challenging for
treating hepatocellular carcinoma (HCC) characterized by high vascularization. Here, it is …

As the clinical efficacy of immunotherapy for triple-negative breast cancer (TNBC) remains
limited, exploring new immunotherapy approaches is still indispensable. Mn 2+ has been …

Chemokines can induce chemotactic cell migration by interacting with G protein-coupled
receptors to play a significant regulatory role in the development of cancer. CXC chemokine …

Abstract Background Dendritic cells (DCs) mediate divergent immune effects by activating T
cells or negatively regulating the immune response to promote immune tolerance. They …

Tumor-draining lymph nodes (TDLNs) are important for tumor antigen–specific T cell
generation and effective anticancer immune responses. However, TDLNs are often the …

Without insight into the correlation between the structure and properties, anion exchange
membranes (AEMs) for fuel cells are developed usually using the empirical trial and error …

Dysregulated cell-cell communication is a hallmark of many disease phenotypes. Due to
recent advances in single-cell transcriptomics and computational approaches, it is now …