The current personalized oncology era has witnessed significant efforts to integrate clinical,
pathological, and molecular classifications. The growing need for molecular biomarkers to …

Context Upper tract urothelial carcinoma (UTUC) represents the third most frequent
malignancy in Lynch syndrome (LS). Objective To systematically review the available …

Purpose: Little is known regarding the prognostic implications of variant histology in upper
tract urothelial carcinoma (UTUC). We sought to evaluate the impact of variant histology …

Upper urinary tract urothelial carcinoma (UTUC) is an uncommon malignancy involving the
renal pelvis and ureter. Careful pathologic analysis plays a critical role in the diagnosis and …

Nested urothelial carcinoma (NUC) and large nested urothelial carcinoma (LNUC) of the
upper urinary tract are exceedingly rare. This has contributed to the paucity of information …

Purpose To evaluate the impact of variant histology on patients with upper tract urothelial
carcinoma (UTUC) survival outcomes. Materials and methods A total of 519 patients …

Accurate pathological staging is crucial for patient management. Patients with T1 bladder
cancer are at risk of recurrence, progression, and death of cancer. Recognition of early …

Context.—Renal malignancies can be divided into cortical-and medullary-based tumors, the
latter of which classically infiltrate the renal parenchyma by extending between …

Nested subtype of urothelial carcinoma (NVUC) of the upper urinary tract is rare. While this
subtype has an aggressive behavior in the urinary bladder, little is known about this subtype …

Tumor budding, defined as a single cancer cell or clusters of fewer than five cancer cells
observed at the tumor invasion front, has been reported to be associated with poor …