[HTML][HTML] Redox regulation of FoxO transcription factors
LO Klotz, C Sánchez-Ramos, I Prieto-Arroyo… - Redox biology, 2015 - Elsevier
Transcription factors of the forkhead box, class O (FoxO) family are important regulators of
the cellular stress response and promote the cellular antioxidant defense. On one hand …
the cellular stress response and promote the cellular antioxidant defense. On one hand …
Global signatures of protein and mRNA expression levels
Cellular states are determined by differential expression of the cell's proteins. The
relationship between protein and mRNA expression levels informs about the combined …
relationship between protein and mRNA expression levels informs about the combined …
Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1
HuR influences gene expression programs and hence cellular phenotypes by binding to
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …
hundreds of coding and noncoding linear RNAs. However, whether HuR binds to circular …
CircInteractome: a web tool for exploring circular RNAs and their interacting proteins and microRNAs
Circular RNAs (circRNAs) are widely expressed in animal cells, but their biogenesis and
functions are poorly understood. CircRNAs have been shown to act as sponges for miRNAs …
functions are poorly understood. CircRNAs have been shown to act as sponges for miRNAs …
AFP promotes HCC progression by suppressing the HuR-mediated Fas/FADD apoptotic pathway
T Chen, X Dai, J Dai, C Ding, Z Zhang, Z Lin, J Hu… - Cell Death & …, 2020 - nature.com
Hepatocellular carcinoma (HCC) is a major leading cause of cancer-related death
worldwide. Alpha fetoprotein (AFP) is reactivated in a majority of hepatocellular carcinoma …
worldwide. Alpha fetoprotein (AFP) is reactivated in a majority of hepatocellular carcinoma …
[HTML][HTML] Circular RNAs as potential biomarkers for cancer diagnosis and therapy
F Wang, AJ Nazarali, S Ji - American journal of cancer research, 2016 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are a naturally occurring type of universal and diverse
endogenous noncoding RNAs which unlike linear RNAs, have covalently linked ends. They …
endogenous noncoding RNAs which unlike linear RNAs, have covalently linked ends. They …
Posttranslational control of HuR function
I Grammatikakis, K Abdelmohsen… - Wiley Interdisciplinary …, 2017 - Wiley Online Library
The RNA‐binding protein HuR (human antigen R) associates with numerous transcripts,
coding and noncoding, and controls their splicing, localization, stability, and translation …
coding and noncoding, and controls their splicing, localization, stability, and translation …
HuR recruits let-7/RISC to repress c-Myc expression
HH Kim, Y Kuwano, S Srikantan, EK Lee… - Genes & …, 2009 - genesdev.cshlp.org
RNA-binding proteins (RBPs) and microRNAs (miRNAs) are potent post-transcriptional
regulators of gene expression. Here, we show that the RBP HuR reduced c-Myc expression …
regulators of gene expression. Here, we show that the RBP HuR reduced c-Myc expression …
[HTML][HTML] HuR function in disease
S Srikantan, M Gorospe - Frontiers in bioscience (Landmark edition …, 2012 - ncbi.nlm.nih.gov
The cytoplasmic events that control mammalian gene expression, primarily mRNA stability
and translation, potently influence the cellular response to internal and external signals. The …
and translation, potently influence the cellular response to internal and external signals. The …
TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1
KK McDonald, A Aulas… - Human molecular …, 2011 - academic.oup.com
TAR deoxyribonucleic acid-binding protein 43 (TDP-43) is a multifunctional protein with
roles in transcription, pre-messenger ribonucleic acid (mRNA) splicing, mRNA stability and …
roles in transcription, pre-messenger ribonucleic acid (mRNA) splicing, mRNA stability and …